The aim of this study was to estimate the burden of childhood rickets-like bone deformity in a rural region of West Africa where rickets has been reported in association with a low calcium intake. A population-based survey of children aged 0.5-17.9 years living in the province of West Kiang, The Gambia was conducted in 2007. 6221 children, 92% of those recorded in a recent census, were screened...

Reports of hypovitaminosis D among adults in the United States have drawn attention to the vitamin D status of children. National data on hypovitaminosis D among children are not yet available. Reports from 2000 and 2001 of rickets among children living in North Carolina, Texas, Georgia, and the mid-Atlantic region, however, confirmed the presence of vitamin D deficiency among some US children ...

1. The diets and living conditions of nin Asian boys with biochemical, and in most instances also radiological, signs of rickets were compared with those of nine other boys who appeared to be normal. The groups were matched according to age, religion, place of father's origin and boy's own place of birth. 2. There were no outstanding differences between the diets of the boys with, and of those ...

CONTEXT The Middle East has a high incidence of rickets, and it is also common in Europe-dwelling children of Middle Eastern origin. OBJECTIVE The objective of the study was to explore the mechanisms leading to rickets in children of the Middle East. DESIGN AND SETTING We conducted a prospective study in 98 rachitic and 50 controls (aged 6 months to 4 yr) from university and community outpa...

Findly (1908) and Mellanby (1919) clearly demonstrated that rickets occurred in young animals fed on a diet containing an insufficient amount of certain substances now known as the “antirachitic vitamine.” As a result of this, the British Medical Research Committee announced that rickets is a deficiency disease due to a lack in the diet of an anti-rachitic factor. For literature up to 1923, cov...

Abstract Purpose Non-ossifying fibromas (NOF) are benign, fibrous lesions of the skeleton estimated to occur in about 30% children and adolescents. In general pediatric population, they twice as common males, usually asymptomatic self-limiting. Etiology is largely unknown, though multiple NOF described with genetic syndromes such neurofibromatosis 1. We have observed various forms rickets. Howe...

Nutritional rickets in children, particularly of Asian immigrants to the U.K., has been well documented over the past 20 years. Its incidence among infafits whose parents are Rastafarians of West Indian origin has not previously been described. In a 3-month period four cases of florid nutritional rickets were discovered at this hospital, and a new 'at-risk' group may have been identified.

Hereditary hypophosphatemic rickets represented by X-linked hypophosphatemic rickets (XLH) is a rare disorder characterized by hypophosphatemia, elevated alkaline phosphatase (ALP) and undermineralization of bone. Active vitamin D and phosphate are administered to correct hypophosphatemia and elevation of ALP. Overtreatment with phosphate leads to secondary hyperparathyroidism, and a large dose...

Hypophosphatemic rickets (HR), also known as refractory, vitamin D resistant rickets, is a hereditary disease linked to the X chromosome. It is characterized by the metabolic disturbance of calcium and phosphate, which causes defective calcifi cation of mineralized structures such as bones and teeth.1,2 It is the most common type of rickets found in developed countries. Its incidence can be cou...

Aim: To investigate the ratio of rickets and vitamin D deficiency in healthy adolescents at Van region. Method: Totally 126 cases were included in this study. All cases were evaluated for the presence of rickets symptoms, daily sun exposure, and vitamin usage, covering and eating habit. Diagnosis of rickets was made based on biochemical findings. The children whose vitamin D levels were lower t...