Background: This article reviews experimental and clinical studies in which neural injuries repaired with bone marrow stromal cells. History: Bone marrow contains two kinds of stem cells: hematopoietic and nonhematopoietic (stromal) stem cell. In vitro studies indicate that bone marrow stromal cells have the capacity of differentiation into other cells (such as neural cell) under treatment wit...

Tumor-reactive T cells, known as tumor-infiltrating lymphocyte(TIL)s are known to infiltrate various tumors. Although TILs exert cytotoxic activities against tumor cells, only a small percentage of tumors usually contain TILs that specifically react to tumor antigens. Because the exact role of these lymphocytes is unclear, we investigated the mechanisms of migration and adhesion of TILs to bone...

OBJECTIVE To estimate the predictable value of histopathologic parameters in chronic rhinosinusitis (CRS) for response to endoscopic sinus surgery (ESS). STUDY DESIGN Symptomatology was rated in 100 patients prior to as well as 12 and 24 months after surgery. Specimens taken during the procedure were examined and scored for goblet cells, subepithelial thickening, mast cells, and eosinophils. ...

Reactivation of latent herpes simplex virus type 1 (HSV-1) infection was induced by UV irradiation of the corneas of latently infected mice. On days 1-4 after stimulation, infectious virus was sought in nervous and ocular tissue. On days 4, 7 and 10, eyes with either recurrent epithelial or stromal disease and appropriate controls were stained to identify immune cells and HSV-1 antigens. The ma...

Reasons for intrastromal corneal ring segment explantation In their recent article, Ferrer et al. report that 57 of 250 implanted intrastromal corneal ring segments (ICRS) had to be explantedda rate of 22.8%. The main cause of this very high explantation rate was extrusion (48.3%). There are 2 major causes of ICRS extrusion: (1) superficial implantation of a segment and (2) a segment that is pl...

PURPOSE To determine the pattern of cytokine production in the cornea and its relationship with viral antigens, in our murine model of recurrent ocular herpes simplex virus (HSV)-1 infection. METHODS Six weeks after corneal inoculation with HSV-1, the eyes of latently infected and control mice were UV irradiated and examined for signs of disease and viral reactivation. The eyes of five mice w...

Hepatocyte growth factor (HGF) exerts proliferative activities in thyrocytes upon binding to its tyrosine kinase receptor c-met and is also expressed in benign thyroid nodules as well as in Hashimoto's thyroiditis (HT). The simultaneous expression of HGF/c-met and three trasducers of tyrosine kinase receptors (STAT3, PI3K, RHO) in both the nodular and extranodular tissues were studied by immuno...

background gastrointestinal stromal tumors (gist) are the most common mesenchymal tumors of the gastrointestinal (gi) tract. they are usually c-kit positive and seen slightly more common in men. these tumors are seen in the gi tract from the esophagus to the anus with occasional invasion or metastasis. method in this retrospective study, we evaluated the prevalence of c-kit positive stromal tum...

let r be an associative ring with unity. an element a in r is said to be r-clean if a = e+r, where e is an idempotent and r is a regular (von neumann) element in r. if every element of r is r-clean, then r is called an r-clean ring. in this paper, we prove that the concepts of clean ring and r-clean ring are equivalent for abelian rings. further we prove that if 0 and 1 are the only idempotents...