CONTEXT The renin-angiotensin system (RAS) interacts with the autonomic nervous system (ANS) in the regulation of blood pressure and cardiovascular function. Several genetic polymorphisms in the RAS have been identified and have been implicated as a cause of hypertension and cardiovascular disease. OBJECTIVE The aim of the present study was to evaluate the relation between genetic polymorphis...

In line with the North Lombok Regency (KLU) government program to prioritize handling and structuring residential areas disaster-prone in Pemenang-Tanjung sub-district 2022, it is necessary carry out several technical studies support program. One of that can be carried an analysis design flood river capacity around Sokong River section Tanjung Village, which a location classified as densely pop...

BACKGROUND Pharmacoepidemiologic analysis can confirm whether drug efficacy in a randomized controlled trial (RCT) translates to effectiveness in real settings. We examined methods used to control for immortal time bias in an analysis of renin-angiotensin system (RAS) inhibitors as the reference cardioprotective drug. METHODS We analyzed data from 3928 patients with type 2 diabetes who were r...

PURPOSE Multiple attempts have been made to improve the clinical/pathologic staging system of Dukes to focus adjuvant therapy decisions. The purpose of this study was to determine whether K-ras mutational status of regional nodes in patients with Dukes B2 colorectal cancer could be used to stage their disease more accurately. METHODS Using formalin-fixed, paraffin-embedded archival material, ...

Abstract. Pokhara (ca. 850 m a.s.l.), Nepal's second-largest city, lies at the foot of Higher Himalayas and has more than tripled its population in past 3 decades. Construction materials are high demand rapidly expanding built-up areas, several informal settlements cater to unregulated sand gravel mining Valley's main river, Seti Khola. This river is fed by Sabche glacier below Annapurna III (7...

Diyala Governorate was recently exposed to high flood waves discharged from Hemrin Dam. Since the dam at its full capacity during period, these were River. Because of reduction in River 750m3/s, cities and villages on both sides river banks inundated. Thus, study's objective is design a escape out River, discharge wave through it. The simulation done by using HEC- RAS software. Two hundred twen...

This paper applies cost-benefit analysis to assess social and private net benefits from rainbow trout European whitefish aquaculture under recirculating system (RAS) marine cage technologies. In addition investment operational costs, we include eutrophication damage nutrients value the fish produced by its producer price. The assessment is made in terms of annualized present benefits. We find t...

A large number of 2D models were originally developed as 1D for the calculation water levels along main course a river. Due to their development distributed models, majority have added precipitation source term. The can now be used quasi-2D hydrodynamic rainfall–runoff (‘HDRRM’). Within direct rainfall method (‘DRM’), there is an approach, referred ‘rain-on-grid’, in which input applied entire ...

The tissue renin-angiotensin system (RAS) has been suggested to be present in human gestational tissues, but uncertainty exists about the authenticity of this RAS, and the cellular origin of this RAS has not been defined. In the present study, we confirmed the presence of authentic renin and angiotensinogen in the prolactin-producing decidual tissue by sequencing the cDNAs generated through rev...

OBJECTIVES To examine nonylphenol (NP) and 4-t-octylphenol (OP) concentrations and general water quality indicators along a river in the greater Tokyo area and to specify the distribution and origin of alkylphenols. METHODS Water was sampled from the Edogawa River, a main river in the greater Tokyo area, which is a source of public drinking water; and the Sakagawa River system, a tributary of...