Ann Saudi Med 29(1) January-February 2009 www.saudiannals.net 55 Lampert and Lennert in 1961 were the first to describe what is now known as Rosai-Dorfman disease (RDD). Subsequently in 1969, Rosai and Dorfman described 4 cases of a disease they called sinus histocytosis with massive lymphadenopathy (better known as RDD).1 In 1972 they analyzed 30 additional cases, establishing RDD2 as a clinic...

Rosai-Dorfman disease (RDD) is a rare condition that causes massive lymphadenopathy, most commonly in the cervical area. Cowden syndrome (CS) hamartomas skin and mucosa predisposes individuals to various malignancies. Lhermitte-Duclos (LDD), or dysplastic cerebellar gangliocytoma, often associated with CS. A 41-year-old female all three conditions presented abnormal uterine bleeding endometrial...