introduction: we aimed at evaluating the clinical, laboratory and echocardiography effects of intracoronary administration of autologous bone marrow stem cell transplantation in different clinical entities of chronic heart failure (hf) patients.   methods: this procedure was carried out during an interventional study conducted in the cardiology department from jan 2012 to apr 2013. the hf patie...

background: we conducted a comprehensive bibliometrics analysis to calculate the h, g, m, a and r indicators for all iranian biomedical research centers (ibrcs) from the output of isi web of science (wos) and scopus between 1991 and 2010. we compared the research performance of the research centers according to these indicators.   methods : this was a cross-sectional and descriptive-analytical ...

objective: cyp2d6, an enzyme, metabolizes a large number of commonly prescribed drugs. variations in cyp2d6 gene encoding this enzyme have been associated with individual differences in drug metabolism rates. the purpose of our study was to identify some allelic variants of cyp2d6 gene and to detect defective cyp2d6 alleles, as part of a pharmacogenetic screening program. materials and methods:...

objective: this study aimed to evaluate the levels of two oxidative stress (os) markers including lipid peroxide (lpo) and total antioxidant capacity (tac) in both serum and follicular fluid (ff) of women with endometriosis after puncture. materials and methods: in this cross-sectional study, a total number of sixty-three women younger than 40 years old with laparoscopy (gold standard for endom...

royan b 1 stem cell can be differentiated to specialized cell types including cardiomyocytes. this developmental change is accompanied with expression of various k + channel types. the aim of this study was to detect functional expression of k + currents from stem cell stage and one week and two weeks after differentiation into cardiomyocyte. mouse stem cell derived cardiomyocytes (es-cardiomyo...

conclusions our study demonstrated that 3d tvs has a good efficacy and reliable agreement with hysteroscopy in diagnosis of uterine lesions among infertile women. therefore, it can decrease the number of diagnostic hysteroscopies. results totally, 153 women were recruited in the investigation. patients aged 30.78 ± 4.79 years in average and the duration of infertility was 4.2 ± 2.91 years among...

introduction: morphology and ultra-structure of myoid and sertoli cells were studied in patients with non-obstructive azoospermia who were admitted to testicular sperm extraction (tese) and intracytoplasmic sperm injection (icsi), by transmission electron microscopy (tem). materials and methods: 12 biopsies of testicular tissues from patients with non-obstructive azoospermia referred to royan i...

background: septins are an evolutionary conserved group of gtp-binding and filament-forming proteins that have diverse cellular roles. an increasing body of data implicates the septin family in the pathogenesis of diverse states including cancers, neurodegeneration, and male infertility. objective: the objective of the study was to evaluate the expression pattern of septin14 in testis tissue of...

objective: to determine the effects of ramadan fasting on serum levels of stress neurohormones in iranian women with polycystic ovary syndrome (pcos). materials and methods: this study was a clinical trial and was performed during july 2011 (month of ramadan) in royan institute, tehran. a total of 40 women who were aged 20-40 years and known cases of pcos and had no other medical diseases were ...