BACKGROUND Turf soil bacterial isolate Delftia sp. VM4 can degrade exogenous N-acyl homoserine lactone (AHL), hence it effectively attenuates the virulence of bacterial soft rot pathogen Pectobacterium carotovorum subsp. carotovorum strain BR1 (Pcc BR1) as a consequence of quorum sensing inhibition. METHODOLOGY/PRINCIPAL FINDINGS Isolated Delftia sp. VM4 can grow in minimal medium supplemente...

Multiple sclerosis (MS) is the autoimmune disease of the central nervous system with complex pathogenesis, different clinical courses and recurrent neurological relapses and/or progression. Despite various scientific papers that focused on early stage of MS, our study targets selective group of late stage secondary progressive MS patients. The presented work is concerned with the reactivity of ...

Multiple sclerosis (MS) is a progressive autoimmune disease of the central nervous system (CNS) in which demyelination, axonal inflammation and damage occurs. The aim of present study was to investigate the influence of matrix metalloproteinase (MMP)-3 5A/6A and its interaction with MMP-7 A-181G polymorphism on the risk and the clinical course of MS. We studied 121 patients and 106 healthy indi...

OBJECTIVES To determine levels of urinary myelin basic protein-like material (MBPLM) in patients with multiple sclerosis (MS) openly treated with interferon beta-1b and to correlate these with clinical changes. BACKGROUND Levels of urinary MBPLM correlate with the presence of the progressive phase of MS and with the disease burden detected on T2-weighted, cranial magnetic resonance imaging. M...

PURPOSE: The purpose of this study is to provide a preliminary assessment of Environmentally Acceptable Lubricants (EALs) for application in dams that are managed by the U.S. Army Corps of Engineers (USACE). The assessment will explore the environmental aspects of these lubricants and will also discuss their operational characteristics. This assessment is primarily through the literature availa...

Joseph M. Betz, PhD Linda Anderson, PhD Mark I. Avigan, MD Joanne Barnes, PhD Norman R. Farnsworth, PhD Barbro Gerdén, MD Leigh Henderson, MS Edward J. Kennelly, PhD Uwe Koetter, PhD Stephanie Lessard, MS Tieraona Low Dog, MD, PhD Michelle McLaughlin, BS Belal Naser, MD Ruediger G. W. Osmers, MD, PhD Linda S. Pellicore, PhD John R. Senior, PhD Richard B. van Breemen, PhD Wolfgang Wuttke, MD Joh...

Alachlor [2-chloro-N-(2,6-diethylphenyl)-N-(methoxymethyl]acetamide] is a chloroacetanilide herbicide and has been widely used as selective pre-emergent post-emergent to control weeds grass. Due its wide usage, direct application on the ground, high solubility in water, moderate persistence, alachlor metabolites have detected various environments. Therefore, there an increasing concern about en...

BACKGROUND AND PURPOSE Disease activity in normal-appearing white matter (NAWM) in multiple sclerosis (MS) has been demonstrated in vivo with T1 relaxation time measurements. We aimed to investigate the spatial distribution of T1 increases in MS NAWM without a priori selection of specific regions. METHODS Whole-brain quantitative T1 maps were measured in 67 patients with one of the 3 main cli...