Sanguisorbae radix (SR), the root of Sanguisorba officinalis L. (Rosaceae), has been traditionally used for its anti-inflammatory, anti-infectious and analgesic activities in Korea. Previous work has shown that SR prevents neuronal cell damage induced by Abeta (25--35) in cultured rat cortical neurons. The present study was carried out to further investigate the neuroprotective effect of SR on ...

Macfarlane Burnet Institute of Medical Research and Public Health, Melbourne, Victoria, Australia; Departamento de Parasitologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brasil; Monash University, Melbourne, Australia; University of Melbourne, Melbourne, Australia. Address correspondence to: Paul Gilson, Brendan Crabb, Macfarlane Burnet Institute for Medical Rese...

Since Ehrlieh and Morgenroth (5) first published their famous horror autotoxicus concept hundreds of observations have been made supporting the idea that the formation of deleterious antibodies against an organism's own antigen is an exceptional event, if possible at all. Investigations on human ABO blood groups have furnished the best. known example of obedience to the biological principle of ...

The phenomenon of tolerance can be said to have begun with the seminal observations in 1945 by R. D. Owen that cattle dizygotic twins display red cell (chimerism--mosaicism as he called it--in adult life. Owen interpreted this extraordinary finding in terms of the much earlier discovery by F. R. Lillie that the placentae of cattle dizygotic twins undergo anastomosis early in fetal life, and he ...

other intellectual, in our population are discussed, and a possible resolution to the conflict is suggested. There are some details of this book whose lack of accuracy might disturb the specialized reader, and this reviewer, who is an obstetrician and gyne-cologist, only hopes that those areas in which he is less informed are more accurate than the sections dealing with aspects of his specialty...

The evolution of sequestration (uptake and accumulation) relative to de novo biosynthesis of chemical defense compounds is poorly understood, as is the interplay between these two strategies. The Burnet moth Zygaena filipendulae (Lepidoptera) and its food-plant Lotus corniculatus (Fabaceae) poses an exemplary case study of these questions, as Z. filipendulae belongs to the only insect family kn...