A pyrazinamidase (PZase)-deficient pncA mutant of Mycobacterium tuberculosis, constructed by allelic exchange, was used to investigate the effects of heterologous amidase gene expression on the susceptibility of this organism to pyrazinamide (PZA) and related amides. The mutant was highly resistant to PZA (MIC, >2,000 microg/ml), in accordance with the well-established role of pncA in the PZA s...

ABSTRACT We present observations of a region the Galactic plane taken during Early Science Program Australian Square Kilometre Array Pathfinder (ASKAP). In this context, we observed scorpio field at 912 MHz with an uncompleted array consisting 15 commissioned antennas. The resulting map covers square ∼40 deg2, centred on (l, b) = (343.5°, 0.75°), synthesized beam 24 × 21 arcsec2 and background ...

BACKGROUND Controversy exists regarding the relationship between radiographic findings and clinical status in knee osteoarthritis. Although the surgical indication for total knee arthroplasty (TKA) should be based on pain, clinical status, and the deterioration of quality of life, the radiographic study is the most commonly used criterion for preoperative evaluation. The objective of this study...

ABSTRACT We present an analysis of the photometric and spectroscopic observations split comet C/2019 Y4 (ATLAS). Observations were carried out on 2020 April 14 16, when heliocentric distance was 1.212 1.174 au, its geocentric 0.998 0.991 phase angle 52.°9 54.°5, respectively. The observed with 6-m BTA (Big Telescope Alt-azimuth) telescope Special Astrophysical Observatory (Russia) SCORPIO-2 (Sp...

ABSTRACT Low- and intermediate-mass stars end their life dispersing outer layers into the circumstellar medium, during asymptotic post-asymptotic giant branch phases. OH masers at 18 cm offer an effective way to probe environment. In this work, we present discovery of seven maser sources likely associated with such evolved from visual inspection Australian SKA Pathfinder (ASKAP) continuum image...

Background. Advanced knee arthritis is indicated for total alloplastic and it is considered to be the method of choice. It allows on abolishing of intensive pain and correcting of efficiency of limb. Material and methods. Postoperative complications were analysed in 109 operated knees in 93 patients. Condylar knee endoprotheses of types AGC I, AGC II, and Scorpio were implanted between 1996 and...

ABSTRACT The low-mass low-surface brightness (LSB) disc galaxy Arakelian 18 (Ark 18) resides in the Eridanus void and because of its isolation represents an ideal case to study formation evolution mechanisms such a type. Its complex structure consists extended blue LSB bright central elliptically shaped part hosting massive off-centred star-forming clump. We present in-depth Ark based on observ...