This paper was commissioned by Professor Gernot Wersig of the Freie Universität, Berlin in 1980, as part of his Project, Methodeninstrumentarium zur Benutzforschung in Information und Dokumentation. It attempted to set out what was, for the time, a novel perspective on appropriate methodologies for the study of human information seeking behaviour, focusing on qualitative methods and action rese...

We describe an “expert coach” for students’ collaborative information seeking and knowledge construction. This coach compares an expert’s prespecification of the evidential relations among “snippets” of HTML-based text with the current state of a diagram constructed by students in the course of collaborative scientific inquiry. The expert advises the students by pointing out information that ma...

The chemistry of lSF has the reputation of being difficult and this is to a large extent supported by a survey of the literature, where there are many reports of reactions involving 18F where the yields are low and the reactions erratic. However, in the nine years since the last review of the chemistry of ~8F in this journal °) considerable progress has been made in understanding and controllin...

A fundamental task within the framework of a project searching for new radiopharmaceuticals for systemic therapy was the evaluation of the capabilities of the Portuguese Research Reactor (RPI) for the production of several important radionuclides. The feasibility of producing 64Cu, 77As, 153Sm, 165Dy, 166Ho, 170Tm, 177Lu, 186Re, 199Au and 111Ag in useful quantities was evaluated for the present...

Quality control (QC) procedures should always be performed following radiopharmaceutical preparation and prior to patient administration. The main aim of QC is to ensure optimal radiopharmaceutical product properties except for some short half-life tracers such as some positron emission tomography (PET) imaging probs. by dispensing a radiopharmaceutical of the highest quality the risk of having...

The Internet has become an important and preferred source of health information. Although the literature has highlighted several key predictors that influence an individual's online health information seeking behavior, insufficient attention has been paid to the changes in the predictors' roles and effects over time. This study explores and compares the effects that specific predictors had on o...

In understanding a person’s information seeking behavior and choice of information sources, it becomes very important to understand the context surrounding the search. This context gives rise to the information need and leads a person to look for information. Research in information seeking behavior, while concentrating on systemand-person centric research, has, so far, left out studying how in...

The ever-growing need for radiopharmaceuticals, i.e., compounds containing pharmaceutical drugs and radioisotopes used medical diagnostic imaging (SPECT/PET scan) treating neoplasms, is significantly leading to an increased demand such substances in hospitals clinics worldwide. Currently, most large-scale productions of required radiopharmaceuticals are carried out research reactors, via the fi...

In spite of considerable progress, much remains to be done in the estimation of absorbed doses to organs and tissues in the body and in the prediction of biological effects from radiopharmaceuticals. In patients undergoing diagnostic procedures, the biokinetics of the radionuclide has to be determined for a number of representative patients. When radiopharmaceuticals are used for therapy, it is...