نتایج جستجو برای: segway personal transporter

تعداد نتایج: 199881  

Journal: :Open Chemistry 2022

Abstract Glutamine transporters transport different amino acids for cell growth and metabolism. In tumor cells, glutamine are often highly expressed play a crucial role in their growth. By inhibiting the acid of these transporters, cancer cells can be inhibited. recent years, more attention has been paid to study transporter. this article, differences between ASC system transporter 2 (ASCT2), L...

Journal: :Journal of Physiological Sciences 2021

Abstract L-type amino acid transporter 2 (LAT2) is a Na + -independent neutral transporter, whose function regulation system remains unclarified. Since protein kinase C (PKC) known to regulate the functions of various transporters, we investigated whether human LAT2 (hLAT2) regulated by PKC. In mouse proximal tubule S2 cells, hLAT2 transport activity was upregulated PKC activation. However, fou...

2014
Yanbing He Shiyuan Xu Junjie Huang Qingjuan Gong

Accumulating evidence has demonstrated that the sodium-potassium-chloride co-transporter 1 and potassium-chloride co-transporter 2 have a role in the modulation of pain transmission at the spinal level through chloride regulation in the pain pathway and by effecting neuronal excitability and pain sensitization. The present study aimed to investigate the analgesic effect of the specific sodium-p...

2016
Farid Yaghouby Sridhar Sunderam

Sleep analysis in animal models typically involves recording an electroencephalogram (EEG) and electromyogram (EMG) and scoring vigilance state in brief epochs of data as Wake, REM (rapid eye movement sleep) or NREM (non-REM) either manually or using a computer algorithm. Computerized methods usually estimate features from each epoch like the spectral power associated with distinctive cortical ...

Journal: :Biomolecules 2021

Astrocytes serve essential roles in human brain function and diseases. Growing evidence indicates that astrocytes are central players of the feedback modulation excitatory Glu signalling during epileptiform activity via Glu-GABA exchange. The underlying mechanism results increase tonic inhibition by reverse operation astroglial GABA transporter, induced Glu-Na+ symport. GABA, released from astr...

Journal: :BMC biotechnology 2016
Thomas S Lane Caroline S Rempe Jack Davitt Margaret E Staton Yanhui Peng Douglas Edward Soltis Michael Melkonian Michael Deyholos James H Leebens-Mack Mark Chase Carl J Rothfels Dennis Stevenson Sean W Graham Jun Yu Tao Liu J Chris Pires Patrick P Edger Yong Zhang Yinlong Xie Ying Zhu Eric Carpenter Gane Ka-Shu Wong C Neal Stewart

BACKGROUND The ATP-binding cassette (ABC) transporter gene superfamily is ubiquitous among extant organisms and prominently represented in plants. ABC transporters act to transport compounds across cellular membranes and are involved in a diverse range of biological processes. Thus, the applicability to biotechnology is vast, including cancer resistance in humans, drug resistance among vertebra...

Journal: :Nature 1902

2018
Monica Fumagalli Livio Provenzi Pietro De Carli Francesca Dessimone Ida Sirgiovanni Roberto Giorda Claudia Cinnante Letizia Squarcina Uberto Pozzoli Fabio Triulzi Paolo Brambilla Renato Borgatti Fabio Mosca Rosario Montirosso

Very preterm (VPT) infants admitted to Neonatal Intensive Care Unit (NICU) are at risk for altered brain growth and less-than-optimal socio-emotional development. Recent research suggests that early NICU-related stress contributes to socio-emotional impairments in VPT infants at 3 months through epigenetic regulation (i.e., DNA methylation) of the serotonin transporter gene (SLC6A4). In the pre...

Journal: :Social cognitive and affective neuroscience 2014
Yina Ma Chenbo Wang Bingfeng Li Wenxia Zhang Yi Rao Shihui Han

Neural activity in the social brain network varies across individuals with different cultural traits and different genetic polymorphisms. It remains unknown whether a specific genetic polymorphism may influence the association between cultural traits and neural activity in the social brain network. We tested whether the serotonin transporter promoter polymorphism (5-HTTLPR) affects the associat...

2018
Hae Won Kim Jee In Kang Eun Hee Hwang Se Joo Kim

Accumulating evidence suggests that the glutamatergic system plays a major role in the pathophysiology of obsessive compulsive disorder (OCD) and empathic processing. Particularly, genetic influence of glutamate transporter gene (SLC1A1) on OCD has been frequently replicated in previous studies, but several studies did not replicate the result. Therefore, we aimed to replicate the associations ...

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