نتایج جستجو برای: sensory neuropathy
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BACKGROUND AND AIM The diagnosis of peripheral diabetic neuropathy is based on clinical examination. Nerve conduction study (NCS) enables earlier diagnosis, but it is demanding and requires specialised personnel. In an attempt to simplify the procedure, this study aimed to identify a new electrophysiological index, which might correlate with results obtained on standardised NCS in patients with...
Taxol is a highly effective anticancer agent that causes peripheral neuropathy as its major toxic side effect. The neuropathy is characterized by degeneration of sensory axons that may be severe enough to be dose limiting. Axonal degeneration involves the activation of the calcium-activated proteases calpains, and here we tested whether systemic inhibition of calpains with the peptide alpha-ket...
Acute autonomic and sensory neuropathy is a rare disorder that has been only anecdotally reported. We characterized the clinical, electrophysiological, pathological and prognostic features of 21 patients with acute autonomic and sensory neuropathy. An antecedent event, mostly an upper respiratory tract or gastrointestinal tract infection, was reported in two-thirds of patients. Profound autonom...
In this issue of J Neurol Neurosurg Psychiatry, the paper by Gorson and colleagues describes 23 patients with neuropathic pain that is distributed in a non-length dependent manner (see page 163). In these patients, neuropathy can be distinguished from conventional length dependent small fibre neuropathy because the sensory disturbance involves proximal regions of the limbs, face and trunk, eith...
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