Inocula, varying from 15 to 1,000 embryonated Capillaria hepatica eggs, were administered to young adult rats by gastric tube, in an attempt to investigate the influence of worm load in the production of septal fibrosis of the liver. Low doses of 15, 30 or 50 eggs were sufficient to produce septal fibrosis, but it appeared with variable degrees of intensity and always with focal distribution. S...

Despite septal myectomy remaining the gold standard septal reduction therapy for hypertrophic obstructive cardiomyopathy (HOCM), there has been a disproportionate use of alcohol septal ablation (ASA) worldwide. Absolute resolution of left ventricular outflow tract (LVOT) obstruction with ASA is not achieved in a substantial proportion of patients. The mechanisms of failure from ASA are partiall...

Hypertrophic cardiomyopathy (HCM) is a cardiac disease associated with a high incidence of atrial fibrillation (AF). Recent studies have suggested that interventricular septum thickness may influence the risk stratification of patients with AF. We evaluated the effects of septal hypertrophy on morbidity and mortality in patients with HCM. Patients were followed for a median of 6.1 years and wer...

It has been previously proposed that a method of distinguishing sinus venosus atrial septal defects from ostium secundum atrial septal defects is a leftward axis deviation (less than +300) of the P waves on the electrocardiograms of patients with sinus venosus defects. The electrocardiograms of i5o patients with surgically corrected atrial septal defects were reviewed to test this proposition. ...

1 Mehmet Emin İnce1, Gökhan Özkan1, Ayhan Kılıç2, Suat Doğancı3, Vedat Yıldırım1 1Department of Anesthesiology and Reanimation, 2Department of Pediatric Cardiology, 3Department of Cardiovascular Surgery, Gulhane Military Academy of Medicine, Ankara, Turkey Pediyatrik Atriyal Septal Defekt için Anestezi / Anesthesia for Pediatric Atrial Septal Defect Anesthesia Management for Transcatheter Atria...

The aim of this study is to determine the percentage of septal deformities in symptomatic patients in Kashmiri population, identified at otolaryngology clinic of a referral & a teaching tertiary care hospital SKIMS Medical College, Bemina, Srinagar, where 429 patients with nasal septal deviation were identified. All of the patients underwent nasal examination by anterior rhinoscope and nasal en...

Reversible inactivation of the medial septal area results in a spatial memory impairment and selective disruption of hilar/CA3, but not CA1, location-specific discharge. The present study examined the possibility that such septal deafferentation produces effects on hippocampal function by altering physiological properties of the primary input and output structures for hippocampus, the entorhina...

Increasing evidence suggests that synchronization between brain regions is essential for information exchange and memory processes. However, it remains incompletely known which synaptic mechanisms contribute to the process of synchronization. Here, we investigated whether NMDA receptor-mediated synaptic plasticity was an important player in synchronization between septal and temporal CA3 areas ...

In several patients with asymmetric septal hypertrophy (ASH) diagnosed by echocardiography (septal-free wall thickness ratios greater than or equal to 1.3), we have discovered marked discrepancies between the echocardiographic and necropsy measurements of wall thicknesses that led to uncertainty regarding the actual cardiac diagnosis. To resolve these apparent incongruities, the echocardiograms...

Atrial septal endocarditis can occur as an isolated event or in association with valvular endocarditis. It is also reported following percutaneous device closure of atrial septal defects. We present the echocardiography findings from a young man presenting with endocarditis of an abnormal mitral valve in whom endocarditis was demonstrated associated with an atrial septal defect.