During a 1-year period (May 1971-May 1972), patients developing the shock syndrome in a large general hospital were referred to a multi-disciplinary shock team. Sepsis, haemorrhage and severe hypoxaemia were the principal precipitating factors. Mortality exceeded 70% in the septic and cardiogenic shock series and was lowest in shock attributable to fluid depletion and drug overdose. Whereas imp...

management strategies for infants and young children with septic shock. Septic shock is diagnosed in the clinical context of suspected infection and persistent signs of decreased perfusion. While antimicrobial therapy is directed against the common age-associated pathogens, “goal-directed” hemodynamic support is the critical focus of resuscitation of the child with septic shock. Aggressive flui...