These last months, dozens of SARS-CoV-2 serological tests have become available with varying performances. A major effort was completed to compare 17 in April 2020 Switzerland. In a preliminary phase, we compared IgG, IgM, IgA and pan Ig including ELISA, LFA, CLIA ECLIA on panel 182 sera, comprising 113 sera from hospitalized patients positive RT-PCR, 69 sampled before 1st November 2019, expect...

Leptospirosis is a zoonosis caused by pathogenic bacteria of the genus Leptospira. This disease affects several animals and humans. Symptoms leptospirosis can range from mild to severe, may in some cases lead death. For diagnosis leptospirosis, microscopic agglutination test considered “gold standard”; however, it has limitations studies are being conducted develop alternative methods screening...

Serological response to louse-borne relapsing fever in Ethiopia was determined by immobilization tests using Borrelia recurrentis cultures. Isolates from 26 patients tested with autologous convalescent sera showed from 90 to 100% of the organisms had been immobilized. Sera from thirteen patients were tested with autologous and heterologous strains. Several reacted with the majority and two show...

Brucellosis is an infectious disease that affects many organ systems. Osteoarticular involvement, especially spondylitis, is the most common complication of brucellosis, but psoas abscess is very rare. Serological tests at diagnosis of the disease are very valuable and most widely used. Herein, we report a case of psoas abscess secondary to brucellar spondylitis. In this case, interestingly, th...

Introduction The year 2006 represented the centenary of the first diagnostic serological test, the Wasserman complement fixation test for the diagnosis of syphilis. In this article I will relate some developments I have observed in the day-to-day running of a diagnostic serology laboratory over the thirty years preceding this centenary. I have assumed some background knowledge and elected to di...

Two hundred and fifty ambulatory patients with febrile respiratory tract infections were included in a prospective study, aimed at determining the reliability of physicians judgements relating to the aetiology of the infection. Compared with advanced serological testing, physicians' judgements for a bacterial/atypical, rather than viral, aetiology had a negative predictive value of 60% and a po...

The remarkable decline in the incidence of syphilis in the first half of the 20th century tempted many observers to share the view of Illingworth (1959) that it was a disappearing disease. Since 1957, however, there has been an unmistakable upward trend in many parts of the world (Stallworthy and Bourne, 1966; Walter and Israel, 1965), and many cases of florid congenital syphilis have been repo...