نتایج جستجو برای: serous tumors
تعداد نتایج: 187057 فیلتر نتایج به سال:
Ovarian cancer is the most common cause of death among women with gynecologic cancer. We examined molecular profiles of fibroblasts from normal ovary and high-grade serous ovarian tumors to identify novel therapeutic targets involved in tumor progression. We identified 2,300 genes that are significantly differentially expressed in tumor-associated fibroblasts. Fibroblast expression of one of th...
Large cell neuroendocrine carcinoma (LCNEC) of the ovary is an uncommon gynaecological malignancy with aggressive clinical course.1 In most instances ovarian LCNEC associated a surface epithelial tumour or mature cystic teratoma.2 Mixed and high grade serous (HGSC) exceedingly rare subentity, only handful cases identified in literature.1 We report case 56-year-old female who presented four week...
Absract A case of 69- year-old woman with large pelvic mass and ascites is reported in this paper. With the exception of mild pelvic pain and a Pelvic mass in pelvic , she had no symptom or sign . All routine and hormonal Lab tests and tumor marker's were normal. The MRI revealed a large mass in anterosuperior of uterus, and left ovary was situated in neighborhood of pelvic mass.Her Uterus nor...
background: to investigate the frequency of different types of gynecological tumors among patients who were operated in shahid sadoughi hospital, yazd, iran, for 3 years. material and methods: this study investigated 101 patients with gynecological tumors from march 21.2008 to march 20 2011.. lesions were considered in 5 groups according to the prevalence of malignancy. lymph node and peritonea...
background and objective: ovarian tumors are among the most frequent pathologic conditions in gynecologic practice and a frequent cause of hospitalization and surgery. the aim of this study was to determine histologic distribution of benign operated masses especially functional ovarian cysts. material and methods: benign ovarian files of operated patients (2961 cases) in 20 tertiary and seconda...
OBJECTIVE To identify the different histopathological types of ovarian neoplasms and their age distribution. METHODS This is a retrospective study were ovarian neoplasms received by the Pathology Department of King Abdulaziz University, Jeddah, Saudi Arabia between January 1995 and December 2010 were reviewed and their frequencies in different age groups were calculated. RESULTS Out of 618...
Purpose. To assess if there is a significant difference in enhancement of high grade serous carcinoma of the ovary compared with other ovarian malignancies on clinically performed contrast enhanced MRI studies. Methods. In this institutional-review-board-approved study, two radiologists reviewed contrast enhanced MRI scans in 37 patients with ovarian cancer. Readers measured the signal intensit...
Ovarian cancer is the leading cause of death from gynecologic cancer. Improvement in the clinical outcome of patients is likely to be achieved by the identification of molecular events that underlie the oncogenesis of ovarian cancer. Here we show that the anaplastic lymphoma kinase (ALK) is aberrantly activated in ovarian cancer. Using an unbiased and global phosphoproteomic approach, we profil...
Approximately 60% of all ovarian tumors are epithelial in origin, and these neoplasms are thought to arise from the ovarian surface epithelium or small epithelial inclusion cysts. Surface epithelium is capable of differentiating into serous (tubal), mucinous, endometrioid or transitional epithelium. Serous and mucinous cystadenomas are the most common epithelial tumors and, together, account fo...
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