Aim: Dendritic cells (DCs) are potent antigen-presenting cells crucial for initiation of cell-mediated immune responses to foreign antigens. They also contribute to the innate resistance against microbial pathogens. The present study examined the effect of microorganisms such as Escherichia coli (E. coli), Serratia marcescens (S. marcescens), Methicillin-resistant Staphylococcus aureus (MRSA), ...

Fertility and immunity are concurrently upregulated in Drosophila melanogaster females after normal mating, potentially requiring physiological trade-offs. Using a novel bacterial introduction method, I observed female copulatory Serratia marcescens receipt and infection. Immuno-competent females surviving copulatory S. marcescens exposure had significantly reduced progeny production during the...

Polymyxin B and rifampin were given to 12 patients with multi-drug-resistant nosocomial Serratia marcescens infections. Eight cures were achieved; drug hepatotoxicity occurred once; one fatal suprainfection was encountered; and two patients died during therapy of causes related to severe underlying illnesses. Polymyxin B and rifampin were uniformly synergistic in vitro against the infecting str...

Serratia marcescens is an opportunistic pathogen that causes a range of human infections, including bacteremia, keratitis, wound infections, and urinary tract infections. Compared to other members of the Enterobacteriaceae family, the genetic factors that facilitate Serratia proliferation within the mammalian host are less well defined. An in vivo screen of transposon insertion mutants identifi...

Prodigiosin, a secondary metabolite extracted from Serratia marcescens (S. marcescens), could induce apoptosis in various cancer cells, with however low toxicity on normal cells. The red pigment was strain S. NJZT-1 isolated soil, which had antibacterial activity. Spectral analyses (LC-ESI-MS, UV-VIS spectrophotometry, infrared spectra and HPLC) TLC indicated the presence of prodigiosin extrace...

Sixty-four patients with malignant diseases from whom Serratia marcescens was isolated from various sources were studied regarding their antibody responses to somatic O antigens of this microorganism. Antibodies were titrated by the passive hemagglutination test. An antibody response was considered present when either a fourfold or greater rise in antibody titers between two consecutive serum s...

β-carotene is a commonly used food colorant. In this work, a novel β-carotene producing strain, Serratia marcescens RB3, was isolated and identified by physiological and biochemical tests, as well as 16S rDNA sequence analysis. The production of β-carotene by S. marcescens RB3 was identified through HPLC analysis. The cultivation conditions for β-carotene production by S. marcescens RB3 were op...

conclusions p. aeruginosa and s. marcescens can be good candidates for the detoxification of cr (vi) in soltan abad river. results the results indicated that pseudomonas aeruginosa and serratia marcescens were the most resistant bacteria with mics of 200 and 150 mg/l, respectively. both bacteria completely reduced 25 and 50 mg/l of cr (vi) in 36 hours and 48 hours, respectively. the growth rate...

The wild strain of Serratia marcescens rapidly degraded threonine and formed aminoacetone in a medium containing glucose and urea. Extracts of this strain showed high threonine dehydrogenase and "biosynthetic" threonine deaminase activities, but no threonine aldolase activity. Threonine dehydrogenase-deficient strain Mu-910 was selected among mutants unable to grow on threonine as the carbon so...

Some strains of S. marcescens are capable of producing pigment, the intensity of which ranges from dark red to pale pink, depending on the age of the colonies. The pigment can be present after incubation at room temperature but usually disappears after subculturing. The pigment was extractred by 1902 and named "prodigiosin" . Serratia marcescens has a predilection for growth on foodstuffs, espe...