introduction and aims: tt virus (ttv) is a dna virus and is proposed as a potential cause of non-a to e hepatitis. we aimed to investigate, for the first time, the prevalence of ttv in iranian healthy blood donors. materials and methods: three hundred and twelve healthy iranian blood donors were randomly selected and tested for ttv dna by the seminested polymerase chain reaction method. serum a...

background: age-related macular degeneration (amd) is one of the leading causes of visual loss among people aged 65 yr and older. the pathophysiology of amd is poorly understood. the purpose of this study was to evaluate the relationship between serum lipid concentrations and age-related macular degeneration. methods: in this case-control study, total cholesterol (tch), low density lipoprotein ...

background glucose is an essential element in the supply of body’s energy. in diseases such as diabetes, glucose increase is associated with disturbance in metabolism. cortisol is an important hormone in the regulation of glucose metabolism, and human serum albumin (hsa) is one of the most important glucose and cortisol transmitters in blood. interaction between albumin and these ligands could ...

in the present study, a comprehensive and systematic strategy was described to evaluate the performance of several three-way calibration methods on a bio-analytical problem. parallel factor analysis (parafac), alternating trilinear decomposition (atld), self-weighted alternating trilinear decomposition (swatld), alternating penalty trilinear decomposition (aptld) and unfolded partial least squa...

strychnos henningsii gilg is recommended among other remedies for the treatment of diabetes in traditional medicine of southern africa. the antidiabetic effect of oral administration of aqueous bark extract of the plant at 125, 250 and 500 mg/kg body weight was investigated in diabetic rats induced with streptozotocin-nicotinamide for 15 days. the extract decreased the blood glucose level, feed...

this study evaluates the effect of preoperative increased level of serum creatinine (cr) on early outcomes after coronary artery bypass graft surgery (cabg). 1140 patients who underwent cabg in our center were studied. patients with cr >2.25 mg/dl or preoperative dialysis and who had off-pump operations were excluded. group 1 consisted of 892 patients with normal cr (0.5-1.2 mg/dl) and group 2 ...

three new rimantadine schiff bases (rsbs) were prepared, and then the interaction of rsbs with bovine serum albumin (bsa) was investigated using fluorescence, synchronous fluorescence, uv-vis absorption spectroscopy under physiological conditions. the results showed that the three rsbs effectively quenched the intrinsic fluorescence of bsa via static quenching. binding constant (ka), number of ...

this study was designed to evaluate serum and milk amyloid a (saa) as an inflammatory indicator in inflammatory diseases. twenty clinically healthy cows and 100 cows with various inflammatory diseases were selected for this study. blood samples were collected from the coccygeal vein of both healthy and diseased groups. milk samples were taken from four quarters of both groups. milk samples of f...

rosa damascena has been traditionally used as an herbal medicine for different therapeutic purposes. inorder to preliminarily study the probable toxic effects of the plant, its infusion was orally administered to 5groups of 5 dogs at doses 0.5-8 times that of human use in traditional medicine (90-1440 mg/kg/d) for 10successive days. the dogs in the control group (n=4) received placebo. serum le...

mechanism of the binding of lomefloxacin (lmf) with human serum albumin has been studied at physiological ph (7.4) using fluorescence spectroscopic technique. lmf is a third-generation fluoroquinolone antibiotic that exhibits striking potency against a broad spectrum of gram-negative and gram-positive bacteria through inhibition of dna gyrase. lomefloxacin is a drug that is excreted in urine an...