Serum levels of glucose, bilirubin, calcium, phosphorus, protein and albumin were measured in a group of nine healthy men before, and on the first, 10th, 20th and 29th day of Rarnadan, and four weeks after Islamic fasting was terminated. There was a significant reduction in body weight, a significant increase in serum bilirubin and a slight decrease in calcium during Ramadan. Serum glucose decr...

BACKGROUND AND PURPOSE Bilirubin is not only a waste end-product but also an antioxidant. Bilirubin is known to be associated with decrease in cardiovascular risk in men, but its relationship to stroke was not clearly understood. METHODS Serum bilirubin concentrations were measured in 78 724 health examinees (41 054 men, aged 30-89 years) from 1994 to 2001. The subjects with potential hepatob...

BACKGROUND AND PURPOSE Circulating bilirubin, a natural antioxidant, is associated with decreased risk of stroke. However, the nature of the relationship between the two remains unknown. We used a Mendelian randomization analysis to assess the causal effect of serum bilirubin on stroke risk in Koreans. METHODS The 14 single-nucleotide polymorphisms (SNPs) (<10-7) including rs6742078 of uridin...

Objective: Oxidative stress and antioxidant deficiency play key roles in the pathogenesis of gastrointestinal damage associated with Crohn's disease (CD). Serum bilirubin, uric acid (UA) albumin are non-enzymatic antioxidants that a role oxidative control. In this study, it was aimed to evaluate change serum UA levels due activity.&#x0D; Material Method: This study designed as single-center, cr...

We describe the cases of four patients who were taking sulfasalazine for inflammatory bowel disease, whose conjugated bilirubin concentrations in serum exceeded their corresponding total bilirubin concentrations as measured with a multilayer film analyzer, the Ektachem 400. Sulfasalazine added to pooled human serum at therapeutic concentrations increased the apparent conjugated bilirubin, as me...

Cord blood from 8,975 babies delivered in Hospital Sultanah Aminah Johor Bahru over a period of eight months (1st August 1985 to 31st March 1986) were screened for G6PD deficiency. The overall incidence was 4.5% in Chinese, 3.5% in Malays and 1.5% in Indian babies. One hundred of these babies were observed in the nursery for seven days and their daily serum bilirubin recorded. The serum bilirub...

In biological systems, once the unconjugated bili­ rubin is released into the plasma, it is transported rather firmly bound to albumin1_3. The binding equilibria of bilirubin to albumin and tissues are of great interest in order to be able to understand the development of hyperbilirubinemia3. It is well established that while the first mole of bilirubin is tightly bound to albumin, the subseque...

Chronic kidney disease (CKD) is a major public health problem. However, few studies have examined the significance of serum bilirubin as a risk factor for the development of CKD in the general Japanese population. The subjects comprised 413 men (mean age: 79±9 years; (range, 60-100 years) and 637 women (mean age: 81±8 years; range, 60-106 years) who visited the medical department of Seiyo Munic...

BACKGROUND The existing therapeutic methods for neonatal jaundice are costly, time-consuming and potentially risky. Zinc salts can reduce phototherapy duration by precipitating unconjugated bilirubin in the intestine (bilirubin and zinc can form a complex in physiologic pH); however, zinc toxicity is an issue that must be considered since theoretically bilirubin reduction by phototherapy may in...