The effects of ethanolic and aqueous extracts of Rheum ribs L. (RR) of the family polygonaceae was studied on serum cholesterol concentration in rabbits. To induce hypercholesterolemia, 0.5 g/kg/day of pure cholesterol powder was given orally to each rabbit for two weeks then cholesterol was halved and each group of animals was treated with a different regimen for another two weeks. Both t...

Normal rabbits were exposed to single, subanesthetitizing doses of chloroform vapors and a regular decrease in their total serum cholesterol was found. In rabbits with abnormally high serum cholesterol levels, however, no consistent changes were observed. In control experiments it was found that in the normal rabbit there is a diurnal variation in serum cholesterol, with lowest values around 4 ...

Enhanced biliary secretion and high faecal excretion of cholesterol are associated with increased cholesterol synthesis in coeliac disease. We have further investigated cholesterol synthesis in coeliac disease by determining the concentrations of faecal steroids and cholesterol precursors in serum, with and without a gluten free diet and while taking cholestyramine. The levels of unesterified m...

We have earlier reported the reduction of total cholesterol, low-density lipoprotein (LDL) cholesterol and oxidized LDL caused by short-term modification of diet with cold-pressed turnip rapeseed oil (CPTRO) instead of butter. The aim of this supplementary study was to determine whether the beneficial effects resulted from altered cholesterol metabolism during the intervention.Thirty-seven men ...

OBJECTIVES The purpose of this research was to determine whether serum plant sterol levels are associated with those in atheromatous plaque. BACKGROUND Cholesterol of low-density lipoprotein (LDL) particles contributes to atheromatous plaque formation; LDL also contains most serum non-cholesterol sterols, including plant sterols. The role of plant sterols in atheromatous plaque formation is o...

In this study we addressed the question whether hypo- and hyper-responders to dietary cholesterol differ with regard to the flexibility of endogenous cholesterol synthesis after changes in cholesterol intake. Whole-body cholesterol synthesis was measured as faecal excretion of neutral steroids and bile acids minus cholesterol intake. In addition, we determined serum concentrations of lanosterol...

Three hundred 1-day old broiler chickens were used to assess the effects of Mucuna leaf meal (MLM) dietary supplementation on performance, haemato-biochemical indices, oxidative status and meat chickens. Five experimental supplemented diets formulated: diets: 1 (0% supplement), 2 (1.1 % OXYT), 3 (0.5% MLM), 4 (1.0 MLM) 5 (1.5% MLM). The final weight gain birds fed was higher (p < 0.05) than ...

This paper will deal exclusively with the relationship between diet and serum cholesterol level. Many publications have appeared in which the role of diet in the production of atherosclerosis and ischaemic heart disease has been discussed. However, in these discussions it is often not sufficiently realized that ischaemic heart disease is a condition of multifactorial origin and that diet and se...

R ecently, the relationship between serum cholesterol and psychiatric disorders had been focused on several psychiatric researches (1-18). High cholesterol levels have been demonstrated in patients with panic disorder (1, 2, 3, 6). An interesting topic is the relationship between cholesterol level and major depression. Low serum cholesterol level in the patients major depression has previously ...

We investigated the changes of cholesterol and non-cholesterol sterol metabolism during plant stanol ester margarine feeding in 153 hypercholesterolemic subjects. Rapeseed oil (canola oil) margarine without (n = 51) and with (n = 102) stanol (2 or 3 g/day) ester was used for 1 year. Serum sterols were analyzed with gas-liquid chromatography. The latter showed a small increase in sitostanol peak...