Murine thioglycollate-elicited peritoneal macrophages were cultured in the presence of a variety of fatty acids added as complexes with bovine serum albumin. All fatty acids tested were taken up readily by the cells and both neutral and phospholipid fractions were enriched with the fatty acid provided in the medium. This generated a range of cells enriched in saturated, monounsaturated or polyu...

BACKGROUND Serum markers of inflammation are candidate biomarkers in multiple sclerosis (MS). ω-3 fatty acids are suggested to have anti-inflammatory properties that might be beneficial in MS. We aimed to explore the relationship between serum levels of inflammation markers and MRI activity in patients with relapsing remitting MS, as well as the effect of ω-3 fatty acids on these markers. MET...

Fatty acids immobilized on agarose have been employed in the isolation and study of serum albumin by affinity chromatography. Various oleyland palmityl-aminoalkylamino-agarose preparations bound about 10 mg of albumin per ml of agarose; other proteins were retained in smaller amounts and with lesser affinity. Fatty acid-agarose columns which had been exposed to human serum and then washed yield...

The possibility that some factor in serum changes the substrate specificity of purified human plasma carboxyl esterase, which hydrolyzes the short chain fatty acid ester, tributyrin, was investigated. The purified carboxyl esterase from human plasma hydrolyzed 48 mmol of tributyrin/mg of protein/h, monoolein at 1560 mumol of released fatty acids/mg of protein/h, diolein at 133 mumol of released...

Dietary fatty acids play a critical role in modulation of airway inflammation in asthma. This study was conducted to compare dietary intakes of essential fatty acids and serum levels of inflammatory factors in asthmatic and healthy adults, and to examine the potential relationship between inflammatory markers and dietary fatty acids. In this case-control study, 47 asthmatic patients (26 males a...

Fatty acids immobilized on agarose have been employed in the isolation and study of serum albumin by affinity chromatography. Various oleyland palmityl-aminoalkylamino-agarose preparations bound about 10 mg of albumin per ml of agarose; other proteins were retained in smaller amounts and with lesser affinity. Fatty acid-agarose columns which had been exposed to human serum and then washed yield...

Rabbits fed on semi-synthetic diets without added cholesterol develop hypercholesterolaemia and a form of atherosclerosis when butter (Wigand, 1959 ; Funch, Krogh & Dam, 1960) or hydrogenated fat (Wigand, 1959) is the sole dietary fat, whereas dietary vegetable oils or fat mixtures having high contents of polyenoic fatty acids increase the serum cholesterol levels only slightly and do not produ...

Background Previous studies have reported inconsistent findings regarding the efficacy of omega-3 fatty acids on pregnant women with major depressive disorder (MDD). This meta-analysis was conducted to systematically evaluate the clinical applicability of omega-3 fatty acids in treating depression in pregnant women. Methods Randomized controlled trials (RCTs) that compared omega-3 fatty acids ...

Phaseolus vulgaris mitochondria incubated in sucrose swell rapidly upon the addition of phospholipase A. Bovine serum albumin inhibits the swelling. The release of free fatty acids as a result of phospholipase A action on the mitochondria is detected only in the presence of bovine serum albumin, which promotes the hydrolysis of both mitochondrial phospholipids and purified lecithin. Either free...

fatty liver is a metabolic disorder of dairy cows in early lactation, and approximately half of multi-parous dairy cows experience a moderate to severe fatty liver at calving. since the occurrence of fatty liver in buffalo is not known, the aim of this study was to evaluate the hepatic content of triacylglycerols (tag) and total lipids (tl), and the serum content of non-esterified fatty acids (...