نتایج جستجو برای: serum metabolites

تعداد نتایج: 359947  

Journal: :Journal of Animal Science and Veterinary Medicine 2022

The purpose of the study was to determine combined efficacy feed additives on growing pigs, performance and digestive tract parameters. experiment conducted for 28 days with 48 male piglets allocated six dietary treatments. Group 1 offered a diet without eubiotic; 2 – acids mixture; 3 phytobiotic, medium-chain fatty (MCFA) yeast; 4 probiotic, MCFA, 5 mixture, sodium butyrate; 6 butyrate. averag...

Journal: :The Journal of biological chemistry 2016
Serena Abbondante Kristin L Eckel-Mahan Nicholas J Ceglia Pierre Baldi Paolo Sassone-Corsi

Diagnosis and therapeutic interventions in pathological conditions rely upon clinical monitoring of key metabolites in the serum. Recent studies show that a wide range of metabolic pathways are controlled by circadian rhythms whose oscillation is affected by nutritional challenges, underscoring the importance of assessing a temporal window for clinical testing and thereby questioning the accura...

Journal: :Clinical chemistry and laboratory medicine 2012
Desirée E C Smith Yvo M Smulders Henk J Blom Julius Popp Frank Jessen Alexander Semmler Melinda Farkas Michael Linnebank

BACKGROUND Disturbances in the levels of one-carbon (1C) metabolism metabolites have been associated with a wide variety of neuropsychiatric diseases. Cerebrospinal fluid (CSF) levels of homocysteine (Hcy) and the other 1C metabolites, nor their interrelatedness and putative determinants, have been studied extensively in a healthy population. METHODS Plasma and CSF samples from 100 individual...

2016
Georgios Grammatikos Niklas Schoell Nerea Ferreirós Dimitra Bon Eva Herrmann Harald Farnik Verena Köberle Albrecht Piiper Stefan Zeuzem Bernd Kronenberger Oliver Waidmann Josef Pfeilschifter

We have recently shown that major alterations of serum sphingolipid metabolites in chronic liver disease associate significantly with the stage of liver fibrosis in corresponding patients. In the current study we assessed via mass spectrometry serum concentrations of sphingolipid metabolites in a series of 122 patients with hepatocellular carcinoma (HCC) compared to an age- and sex-matched seri...

2011
Koji Fujita Koichiro Wada Yuichi Nozaki Masato Yoneda Hiroki Endo Hirokazu Takahashi Hiroyuki Kirikoshi Masahiko Inamori Noritoshi Kobayashi Kensuke Kubota Satoru Saito Atsushi Nakajima

BACKGROUND A visceral fat area of more than 100 cm2 as measured by computed tomography (CT) at the umbilical level has been included as a criterion for obesity in all the proposed criteria for metabolic syndrome. However, CT cannot be used frequently because of radiation exposure. We evaluated the usefulness of measurement of the serum levels of nitric oxide (NO), instead of CT and the waist ci...

Journal: :Obesity facts 2012
Simone Wahl Zhonghao Yu Michaela Kleber Paula Singmann Christina Holzapfel Ying He Kirstin Mittelstrass Alexey Polonikov Cornelia Prehn Werner Römisch-Margl Jerzy Adamski Karsten Suhre Harald Grallert Thomas Illig Rui Wang-Sattler Thomas Reinehr

OBJECTIVE The human serum metabolite profile is reflective of metabolic processes, including pathophysiological changes characteristic of diseases. Therefore, investigation of serum metabolite concentrations in obese children might give new insights into biological mechanisms associated with childhood obesity. METHODS Serum samples of 80 obese and 40 normal-weight children between 6 and 15 ye...

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