OBJECTIVES We tested the hypothesis that serum total testosterone and sex hormone-binding globulin (SHBG) levels predict cardiovascular (CV) events in community-dwelling elderly men. BACKGROUND Low serum testosterone is associated with increased adiposity, an adverse metabolic risk profile, and atherosclerosis. However, few prospective studies have demonstrated a protective link between endog...

INTRODUCTION AND OBJECTIVES The best indicators to the diagnosis of hypogonadism are free and bioavailable testosterone circulating levels. Free and bioavailable testosterone measurements are complex. However, simple kits for direct measurement of free testosterone by analog immunoassay are available. We examined the utility of an enzymoimmunoassay kit for free testosterone measurement. MATER...

objective: spinal cord injury (sci) causes infertility in male patients through erectile dysfunction, ejaculatory dysfunction, semen and hormone abnormalities. oxidative stress (os) is involved in poor semen quality and subsequent infertility in males with sci. the aim of this study is to examine the effects of sci on the level of testosterone hormone. materials and methods: in this experimenta...

BACKGROUND AND OBJECTIVES Deterioration of kidney function impairs testosterone production, with hypogonadism being common in men with chronic kidney disease (CKD). In nonrenal populations, testosterone is suggested to participate in the atherosclerotic process. In male dialysis patients, we showed that low testosterone increases the risk of mortality. We here studied plausible links among test...

Seminal plasma (SP) plays an important role in the motility, viability and maintenance of the fertilizing capacity of mammalian spermatozoa. This study is the first on brown bear (Ursus arctos) SP components, and has two main objectives: 1) to define the SP composition in bear ejaculate and 2) to identify variations in SP composition in relation to high and low levels of testosterone in serum d...

BACKGROUND Polycystic ovarian syndrome (PCOS) is a heterogeneous endocrine disorder affecting women of reproductive age. The syndrome is characterized by a combination of polycystic ovarian morphology, clinical features and biochemical indices. The objective of this prospective observational study was to investigate the relationship between the total ovarian volume and the ovarian stromal volum...

Stressful experiences include major life events, trauma, and abuse and are sometimes related to the environment in the home, workplace, or neighborhood. Acute stress and chronic can both have long-term consequences. Therefore, this study was carried out to investigate cortisol, total testosterone and total homocysteine (tHcy) status in acute myocardial infarction (AMI). Thirty AMI patients were...

Objectives: Studies suggest a beneficial effect of transdermal testosterone (TT) used prior to controlled ovarian stimulation (COS) on reproductive outcomes in poor responders. Our aim was evaluate the adverse effects and serum concentrations testosterone, sex hormone-binding globulin (SHBG), estradiol, following new TT dosage associated with combined oral contraceptive (COC) before COS Methods...

OBJECTIVES To understand the factors that influence joint cartilage in health and disease as they are important for the prevention and management of osteoarthritis. METHODS We conducted a cross-sectional study to determine factors influencing knee cartilage volume in 45 males aged (mean+/-S.D.) 52.5+/-13.2 yr. RESULTS Total and medial tibial volumes were inversely associated with age, body ...

This study was performed to establish the changes in the level of some serum hormones (Follicle stimulating hormone "FSH", Leutinizing hormone "LH" and testosterone) as well as to determine the changes in the concentrations of some testicular lipid parameters (viz., total cholesterol and total triacylglycerols) of infected mice with Schistosoma mansoni for different periods of time. Electron mi...