Sequence-based domain assignment is one of the most important and challenging problems in structural biology. We have developed a method, CHOP, that chops proteins into domain-like fragments. The basic idea is to cut proteins from entirely sequenced organisms beginning from very reliable experimental information (Protein Data Bank), proceeding to expert annotations of domain-like regions (Pfam-...

In this paper we study the preemptive assignment of a single server to two queues. Customers arrive at both queues according to Poisson processes, and all service times are exponential, but with rates depending on the queues. The costs to be minimized consist of both holding costs and switching costs. The limiting behavior of the switching curve is studied, resulting in a good threshold policy....

We consider a system of parallel servers handling users of various classes, whose service rates depend not only on user classes, but also on the set of active servers. We investigate the stability under two types of allocation strategies: (i) server assignment where the users are assigned to servers based on rates, load, and other considerations, and (ii) coordinated scheduling where the activi...

We consider scheduling soft real-time tasks for a cluster which consists of multiple servers. Each server provides identiccal services where an incoming task can be assigned to one of the servers. The question we investigate is which assignment produces the best performance given two alternattive approaches to queue the arriving tasks: a centralized approach or a distributed one. A missed deadl...

Recently, both academia and industry have initiated research projects directed on integration of P2PSIP paradigm into communication systems. In this paradigm, P2P network stores most of the network information among participating peers without help of the central servers. The concept of self-configuration, self-establishment greatly improves the robustness of the network system compared with th...

Assignment model is a powerful operations research techniques that can be used to solve assignment or allocation problem. This study applies the assignment model to the course allocation problem in Nigeria tertiary institution in order to maximize lecturers’ effectiveness. A well-structured questionnaire was used to obtain data from lecturers and solved with Hungarian method. The study revealed...

Distributed processing systems are considered to solve the challenging requirements of trigger and data acquisition systems for future HEP experiments. The aim of this work is to present a software environment to control and monitor large scale parallel processing systems based on a distributed client-server approach developed in Java. One server task may control several processing nodes, switc...

ProDom contains all protein domain families automatically generated from the SWISS-PROT and TrEMBL sequence databases (http://www. toulouse.inra.fr/prodom.html ). ProDom-CG results from a similar domain analysis as applied to completed genomes (http://www.toulouse. inra.fr/prodomCG.html ). Recent improvements to the ProDom database and its server include: scaling up to include sequences from Tr...