A new sesquiterpene of humulene type, named 2beta, alpha-epoxy-6Z, 9Z-humuladien-8alpha-ol (1) together with a known compound lactarinic acid was isolated from the fruiting bodies of Lactarius hirtipes. Their structures were established on the basis of spectral evidence (MS, IR, NMR, HMBC, HMQC, 1H-1H COSY, ROSEY experiments). Compound 1 was found as the first humulene-type sesquiterpene in hig...

Sesquiterpene lactones (SLs) are a group of secondary metabolites that represent a diverse and unique class of natural products and are important constituent of essential oils, formed from head-to-tail condensation of three isoprene units and subsequent cyclization and oxidative transformation to produce a cis or trans-fused lactone. In this editorial we are going to focus on anticancer, anti-i...

family cupressaceae is the largest coniferous plant family. essential oils of many species belonging to family cupressaceae are known to have several biological activities specially antimicrobial activity. the essential oils from aerial parts of calocedrus decurrens torr., cupressus sempervirens stricta l. and tetraclinis articulata (vahl) mast. were prepared by hydrodistillation. the chemical ...

The antifungal activity of 40 coumarins was tested against the fungal strains: Candida albicans (ATCC 14053), Aspergillus fumigatus (ATCC 16913) and Fusarium solani (ATCC 36031), using the broth microdilution method. Osthenol showed the most effective antifungal activity among all the compounds tested, with a MIC value of 125 microg/ml for Fusarium solani and 250 micro/ml for Candida albicans a...

The antibacterial activity of coumarin per se and other 45 coumarin derivatives was tested against strains of Bacillus cereus MIP 96016, Escherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC 27853, and Staphylococcus aureus ATCC 25923. The inhibitory effects of coumarins were affected by their substitution patterns. Osthenol (44) showed the most effective antibacterial activity against Gram-...

The fruits of Garcinia scortechinii afforded 10 new compounds: four caged-tetraprenylated xanthones (scortechinones Q-T, 1-4), four rearranged xanthones (scortechinones U-X, 5-8), and two sesquiterpene derivatives (scortechterpenes A, B, 9, 10), together with 14 known compounds: one sesquiterpene, two biflavonoids, and 11 caged-polyprenylated xanthones. Their structures were elucidated by analy...

The sesquiterpene compounds present in red wines were characterized and quantified by Headspace Solid-Phase Microextraction in combination with Gas Chromatography–Mass Spectrometry (HS-SPME-GC-MS). Sixteen sesquiterpenes were identified, mainly hydrocarbons but also derived oxygenated compounds. Sesquiterpenes were acyclic, monocyclic, byciclic and tryciclic. Sesquiterpenes were detected in SIM...