The zebrafish dorsoventral axis can first be distinguished at gastrulation, upon formation of the embryonic shield, the site of the organizer. We have asked whether the shield is specified before gastrulation. First, we show that brief exposure of premidblastula embryos to lithium, which is known to shut down the phospho-inositol signaling pathway, produces excessive shield formation and extrem...

In the last decade, numerous growth factors and biomaterials have been explored for the treatment of myocardial infarction (MI). While pre-clinical studies have demonstrated promising results, clinical trials have been disappointing and inconsistent, likely due to poor translatability. In the present study, we investigate a potential myocardial regenerative therapy consisting of a protein-engin...

Reinforcement learning algorithms discover policies that maximize reward, but do not necessarily guarantee safety during learning or execution phases. We introduce a new approach to learn optimal policies while enforcing properties expressed in temporal logic. To this end, given the temporal logic specification that is to be obeyed by the learning system, we propose to synthesize a reactive sys...

Biofertilizer Ning shield was composed of different strains of plant growth promotion bacteria. In this study, the plant growth promotion and root-knot nematode disease control potential on Trichosanthes kirilowii in the field were evaluated. The application of Ning shield significantly reduced the diseases severity caused by Meloidogyne incognita, the biocontrol efficacy could reached up to 51...

For shielding applications that cannot sufficiently be shielded by only a passive shield, it is useful to combine a passive and an active shield. Indeed, the latter does the “finetuning” of the field reduction that is mainly caused by the passive shield. The design requires the optimization of the geometry of the passive shield, the position of all coils of the active shield, and the real and i...

Scalability issues may prevent users from verifying critical properties of a complex hardware design. In this situation, we propose to synthesize a “safety shield” that is attached to the design to enforce the properties at run time. Shield synthesis can succeed where model checking and reactive synthesis fail, because it only considers a small set of critical properties, as opposed to the comp...

background: heat stress is one of the agents in the work environment that can create numerous problems for workers. the objective of this research is to study heat stress control in the foundry platform of a steel plant in tehran. methods: in this experimental study, controlling plans were demonstrated for the work conditions improvement in one of steel plant's foundry platforms. for controllin...

Background: The use and effectiveness of traditional lead gonad shields in pediatric pelvic radiography has been challenged by several literatures over the past two decades. The aim of this study was to develop a new radioprotective gonad shields to be use in pediatric pelvic radiography. Materials and Methods: The commercially available 0.06 mm lead equivalent bismuth garment has cropped squar...

Background: Gonad shielding has been recommended during pelvic x-rays since the 1950s. The popular method of gonad shielding is placement a lead shield in the midline of the pelvis. The aim of this study was to evaluate the prevalence and utility of gonad shielding in pediatrics undergoing pelvic x-rays.Materials and MethodsFollowing study approval, we retrospectively retrieved data from the di...

Introduction: Recently, the use of nanoparticles has increased for many purpose in medicine. One of these is using the nano particles in shields structure to protect sensitive organs such as breast which placed inside the field of chest CT scan and receives high dose. The aim of this study was the use of nano Bi2O3 to making shield for protection breast in chest CT examination ...