Euphorbia thymifolia (Euphorbiaceae) is a prostrate herb, distinguished from similar species by the combination of serrate leaf margin, puberulous ovary/fruit with capitate styles and pedicel not accrescent in fruit, splitting involucre cyathia during maturation. In this paper we present first record E. for state Acre, Alto Juruá region, municipality Cruzeiro do Sul, residential sidewalk crack ...