INTRODUCTION Pelvic ring fractures are severe injuries whose functional results depend on the quality of reduction. Numerous internal fixation alternatives have been described, but the biomechanical studies comparing them remain rare. HYPOTHESIS This study compared the biomechanical behavior of iliosacral screws (ISS) with sacroiliac hinge type fixation (SIF) following unstable pelvic ring fr...

Accurately quantifying gross primary production (GPP) is of vital importance to understanding the global carbon cycle. Light-use efficiency (LUE) models and process-based models have been widely used to estimate GPP at different spatial and temporal scales. However, large uncertainties remain in quantifying GPP, especially for croplands. Recently, remote measurements of solar-induced chlorophyl...

Vegetation phenology is a key indicator of vegetation-climate interactions and carbon sink changes in ecosystems. Therefore, it very important to understand the temporal spatial variability vegetation driving climatic determinants [e.g., temperature (Ts) soil moisture (SM)]. greenness photosynthetic were derived using double logistic (DL) method enhance index (EVI) solar-induced chlorophyll flu...

Adrenal chromaffin cells, sympathetic neurons, and small intensely fluorescent (SIF) cells are each derived from the neural crest, produce catecholamines, and share certain morphological features. These cell types are also partially interconvertible in cell culture (Doupe et al., 1985a,b; Anderson and Axel, 1986). Thus, these cells are said to be members of the sympathoadrenal (SA) lineage and ...

Polymethylmethacrylate (PMMA) coated microcapsules of diclofenac sodium (DFS) were prepared by a modified water-in-oil-in-water (W1/O/W2) emulsion solvent evaporation method using sodium alginate (SAL) as a matrix material in the internal aqueous phase (W1). Their performance with respect to controlled release of the drug in simulated gastric fluid (SGF) and simulated intestinal fluid (SIF) wer...

BACKGROUND Illicit drug overdose remains a leading cause of premature mortality in urban settings worldwide. We sought to estimate the number of deaths potentially averted by the implementation of a medically supervised safer injection facility (SIF) in Vancouver, Canada. METHODOLOGY/PRINCIPAL FINDINGS The number of potentially averted deaths was calculated using an estimate of the local rati...

The purpose of this study is to develop novel intestinal-specific drug delivery systems with pH sensitive swelling and drug release properties. Methacrylic-type polymeric prodrugs were synthesized by free radical copolymerization of methacrylic acid, poly(ethyleneglycol monomethyl ether methacrylate) and a methacrylic derivative of N-(4-hydroxyphenyl)-2-(4-methoxyphenyl) acetamide in the presen...

MOTIVATION Understanding gene regulation in biological processes and modeling the robustness of underlying regulatory networks is an important problem that is currently being addressed by computational systems biologists. Lately, there has been a renewed interest in Boolean modeling techniques for gene regulatory networks (GRNs). However, due to their deterministic nature, it is often difficult...

Determining the spatial and temporal distribution of terrestrial gross primary production (GPP) is a critical step in closing the Earth’s carbon budget. Dynamical global vegetation models (DGVMs) provide mechanistic insight into GPP variability but diverge in predicting the response to climate in poorly investigated regions. Recent advances in the remote sensing of solar-induced chlorophyll flu...

Glacial algae blooms on the Greenland ice sheet darken surface albedo, enhancing melt. Sentinel-3 data was first to highlight extent of these blooms, which are expected become larger as climate changes. Here we propose a novel use solar-induced chlorophyll fluorescence (SIF) from TROPOMI confirm Sentinel-based maps and extend daily levels understand year-to-year variations in blooms. We combine...