A 53-year-old woman who had undergone aortic valve replacement with a Starr-Edwards (S-E) valve (Model 1260) and open mitral commissurotomy 28 years previously was hospitalized with cardiac failure. Echocardiography showed mitral stenosis, mitral regurgitation, and a normally functioning S-E prosthesis. At reoperation, the mitral and aortic valves were replaced with St Jude bileaflet mechanical...

The partial agonistic role of impeding estrogens is further described. Synthesis of progesterone receptor, induced with estradiol, is inhibited by appropriate doses of estriol or 16-epiestriol. Inhibition of 7.12-dimethylbenz(a)anthracene-induced rat breast tumors by estriol was observed. Silastic tubing implants containing estriol markedly reduced tumor takes and delayed onset of first tumors....

Cannulae containing testosterone proprionate (T) were bilaterally implanted into the medial preoptic area (MPO), the ventral tegmental area (VTA), or both areas concurrently (MPO/VTA) of castrated male house mice. A fourth group of castrates in which the intracranial implants missed their targets (MIMP) served as controls. In addition, other castrates were implanted subcutaneously with empty si...

OBJECTIVE To analyze the incidence of prolonged epiphora after maxillectomy according to transected nasolacrimal duct management technique, type of tumor, radiotherapy, and timing of tube removal and performance of dacryocystorhinotomy. DESIGN Retrospective medical record review. Settings University hospitals. PATIENTS We studied 89 patients (90 cases) who underwent nasolacrimal duct transe...

BACKGROUND The occurrence of a snare-related stenosis after beating-heart surgery prompted the search for an alternative method of hemostasis. Because of the shortcomings of commercial coronary shunts a novel custom-made coronary shunting technique was devised. It involves the use of varying lengths of 1.2-mm Silastic tubing secured with a fine silk "tag" suture. The technique of construction a...

The influence of deoxycorticosterone acetate (DOCA) on the sodium content of the red blood cell was determined in the pig. DOCA (100 mg/kg), impregnated in Silastic, was implanted subcutaneously (s.c.) in six male pigs; seven additional pigs received Silastic implants without the DOCA. Those receiving DOCA had an increase in mean arterial pressure (MAP) that was significant in 48 hours and reac...