In the first article of this series of two we discussed several aspects of the clinical performance of silicone hydrogel (SiH) materials and currently available lenses. In addition to looking at the oxygen performance, the evidence for potentially reduced symptoms of discomfort and end of day dryness with SiHs was examined. In this second article, we will look at additional aspects of SiH mater...

PURPOSE To employ confocal microscopy to investigate the etiology of keratocyte loss after short-term contact lens wear by monitoring quantitative changes in keratocyte density. METHODS Twenty neophyte subjects aged 26 +/- 3 years participated in the study, which was conducted over the course of three experimental sessions. In the first session, one eye of each subject was fitted with a silic...

in view of the rapid expansion of contact lens amongst the users, new dimensions have been added to the domain of ophthalmology: giant papillay conjunctivitis, a disease caused by different kinds of contact lens, appears weeks or months after they are used, although some patients are struck years later. the predominant symptoms are increased awareness of lenses, ocular itching, blurred vision a...

PURPOSE To evaluate ocular response and subject acceptance of a new multipurpose disinfecting solution (MPDS), Complete Revitalens (RevitaLens OcuTec in the US Market), for soft contact lens care in a large "real practice" setting. METHOD This is an international multi-center, open-label assessment carried out in 10 countries across Europe and in the USA. Up to 10 subjects who were currently ...

PURPOSE Toll-like receptor 4 (TLR4), a member of the TLR family, is an important pattern recognition molecule that plays a role in the host's innate immune responses to lipopolysaccharide (LPS), a component of gram-negative bacteria. Contact lens wear is one of the risk factors for bacterial keratitis. The purpose of this study was to determine whether hypoxia or contact lens wear alters the TL...

Ten brands of hydrogel contact lenses were selected from five of the six British Approved Name lens classification groups to test in vitro the effects of repeated heat disinfection by means of microwave irradiation. Each lens type was tested over a number of cycles corresponding to its scheduled number of wearing days. The total diameter and back vertex power of all 80 test and 12 control lense...