BACKGROUND The aim of this study was to characterize the efficacy of nano-hydroxyapatite-coated silk fibroin constructs as a scaffold for bone tissue engineering and to determine the osteogenic effect of human dental pulp and periodontal ligament derived cells at an early stage of healing in rabbits. 3D silk fibroin constructs were developed and coated using nano-hydroxyapatite crystals. Dental...

BACKGROUND Sericulture plays an eminent role in development of rural economy in India. Silk filature is a unit where silk is unwound from the cocoons and the strands are collected into skeins. During the process workers are exposed to the high molecular weight proteins like Sericin and Fibroin which are potent allergens leading to sensitization over a period of time and subsequently occupationa...

Introduction: Transglutaminase-mediated polymerization, unlike the traditional restoration methods based on the application of synthetic polymers, has proved to be a potential strategy in the restoration of historic silk. In the present study, the treatment process has been adapted to satisfy the needs of consolidating historic silk fabrics in various cases. Artificially aged (dry thermal agein...

Silk fibroin has attracted great interest in tissue engineering because of its outstanding biocompatibility, biodegradability and minimal inflammatory reaction. In this study, two kinds of biocomposites based on regenerated silk fibroin are fabricated by electrospinning and post-treatment processes, respectively. Firstly, regenerated silk fibroin/tetramethoxysilane (TMOS) hybrid nanofibers with...

Spider dragline silk is a natural fiber that has excellent tensile properties; however, it is difficult to produce artificially as a long, strong fiber. Here, the spider (Araneus ventricosus) dragline protein gene was cloned and a transgenic silkworm was generated, that expressed the fusion protein of the fibroin heavy chain and spider dragline protein in cocoon silk. The spider silk protein co...

Stenopsyche marmorata larvae spin underwater adhesive silk for constructing nests and capture nets. The silk can be divided into fiber and adhesive regions, according to their function. The silk fiber region has a two-layer structure: a core layer situated at the center of the fiber and S. marmorata fibroin, the major component of the silk. In the anterior part of the anterior silk gland, the m...

introduction: glass-ionomer cements (gics) are one of the most important dental restorative biomaterials. the aim of this study was to synthesize glass-ionomer‒silk fiber composite and evaluate the effect of adding natural degummed silk fiber on the bioactivity and the ability to release fluoride by glass-ionomer cement. materials and methods: in this study, commercial fuji ii glass-ionomer cem...

Albeit silks are fairly well understood on a molecular level, their hierarchical organisation and the full complexity of constituents in the spun fibre remain poorly defined. Here we link morphological defined structural elements in dragline silk of Nephila clavipes to their biochemical composition and physicochemical properties. Five layers of different make-ups could be distinguished. Of thes...

THE colours and forms of moths and butterflies have inspired artists and poets for centuries. One of the oldest industries to evolve from insects is sericulture, or silk production. According to Confucius' records, silk was discovered in the third millennium B.C. in China. The Chinese held a monopoly over silk to the extent that anyone attempting to export silk came under the death sentence by ...

Abstract In this paper, we report silk fibroin (SF) and carbon quantum dots (CQDs) nanocomposites obtained through a facile solution casting approach. The optical properties of the have been characterised by UV–vis absorption photoluminescence spectroscopy. Crosslinking SF chemical interactions with CQDs investigated FTIR addition, water stability degradability prepared composites in terms mass...