the synthesis of diethyl/methyl 1,3-diaryl-1,2,3,6-tetrahydro-pyrimidine-4,5-dicarboxylates can be achieved using one-pot reaction from dialkylacetylene dicarboxylate, amines, and formaldehyde by employing hydrated phosphomolybdic acid (h3[p(mo3o10)4].xh2o) as catalyst at room temperature. the effect of various solvent and catalyst amount was investigated. the salient features of the present me...

a highly efficient protocol has been developed for the synthesis of 2-hydrazolyl-4-thiazolidinone derivatives installing a one pot three component coupling reaction of an aromatic aldehyde, thiosemicarbazide and maleic anhydride using guanidine hydrochloride as highly inexpensive and environmentally friendly catalyst under solvent free condition at 1200c with good to excellent yields, it offers...

a rapid and efficient one-pot, four-component protocol towards the synthesis of polyhydroquinoline derivatives has been developed. the condensation of aldehyde, dimedone, ethyl acetoacetate and ammonium acetate in presence of stannous chloride was carried out under solvent free condition to synthesize a variety of polyhydroquinoline derivatives in good to excellent yields. stannous chloride was...

a simple and efficient method for the chemoselective 1,1-diacetate protection of aromatic aldehydes with acetic anhydride by using ni2+ supported on hydroxyapatite-core-shell magnetic γ-fe2o3 nanoparticles (γ-fe2o3@hap-ni2+) under solvent free conditions. this method has several advantages, including high yield, short reaction time, simple work-up and recyclable property of the catalyst. the ca...

Neuromotor reaction times (simple, choice, and decision) were measured when Thyrotropin-releasing hormone (TRH) was administered intravenously to nine healthy men in a double-blind study. Measurements were made of simple reaction time, choice reaction time, and decision time for each subject at various intervals over a 54-hr. period. Given the observed inherent interaction of the drug with the ...

Visual and auditory simple reaction times were measured in Sri Lankan young adults to see the effect of dual-tasking on reaction time. Reaction times were measured using a reaction time program in a computer. Subjects responded to stimuli by pressing the spacebar with their dominant index finger. Visual and auditory simple reaction times (ms) in males (mean ± SD) were 293.5 ± 42.4, 302.2 ± 41.9...