A novel operation mode for time of flight-secondary ion mass spectrometry (ToF-SIMS) is described for a TOF.SIMS 5 instrument with a Bi-ion gun. It features sub 100 nm lateral resolution, adjustable primary ion currents and the possibility to measure with high lateral resolution as well as high mass resolution. The adjustment and performance of the novel operation mode are described and compare...

This paper presents a set of data which compares the potential and limitations of laser microprobe mass spectrometry (TOFLMMS and FT-LMMS) and static secondary ion mass spectrometry (S-SIMS) for inorganic speciation at a microscopical level. In general LMMS yields prominent signals of adduct ions consisting of the intact molecule combined with a stable ion, which allows a direct identification ...

This paper presents our research work to develop an advanced Selfadaptive Intelligent Monitoring System (SIMS) to help patients, families and clinicians manage chronic conditions associated with heart failure more effectively at home. SIMS takes advantages of a number of advanced technologies from software intelligence, data/knowledge retrieval, data mining and database. SIMS is able to provide...

This paper outlines how representations of gender, sexuality, race and ethnicity intersect with strategies of late capitalism in The Sims, arguably the most popular video game of all time. Within an industry known for its social stereotyping, The Sims has been praised as socially progressive for its liberal views towards same-sex relationships, racial equality, and nonsexualized presentation of...

This Perspective aims to inform the heterogeneous catalysis and materials science community about the recent advances in Time-of-Flight-Secondary Ion Mass Spectrometry (ToF-SIMS) to characterize catalytic solids by taking large model H-ZSM-5 zeolite crystals as a showcase system. SIMS-based techniques have been explored in the 1980-1990's to study porous catalyst materials but, due to their lim...

The suitability of in situ Secondary Ionisation Mass Spectrometry (SIMS) techniques for measuring O isotopes in speleothems is critically examined by applying this technique to a 500-year interval of the well-known Hulu Cave record (Wang, Y.J., Cheng, H, Edwards, R.L., An, Z.S., Wu, J.Y., Shen, C.C., Dorale, J.A., 2001. A high-resolution absolute dated late Pleistocene monsoon record from Hulu ...

Mass spectrometry imaging (MSI) is a versatile tool for visualizing molecular distributions in complex biological specimens, but locating microscopic chemical features of interest can be challenging in samples that lack a well-defined anatomy. To address this issue, we developed a correlated imaging approach that begins with performing matrix-assisted laser desorption/ionization (MALDI) MSI to ...

My paper is based on the idea that computer games as simulations can be seen as a new kind of aesthetical realism forming a certain perception of reality and thus certain ideological statements. These statements can be found in the structural shaping of the games, in other words the rules and gameplay of a game. The investigation thus concerns the framework that the rules and gameplay provide i...