PURPOSE This study compared serum vascular endothelial growth factor (VEGF) concentration between patients given the bilateral and unilateral intravitreal injections of bevacizumab. METHODS In a prospective manner, serum VEGF levels in treatment-naive patients with age-related macular degeneration who underwent bilateral or unilateral intravitreal injections of bevacizumab were investigated. ...

Production strategy from a hydrocarbon reservoir plays an important role in optimal field development in the sense of maximizing oil recovery and economic profits. To this end, self-adapting optimization algorithms are necessary due to the great number of variables and the excessive time required for exhaustive simulation runs. Thus, this paper utilizes genetic algorithm (GA), and the objective...

INTRODUCTION Peptic ulcer remains the most frequent cause of upper gastrointestinal bleeding. Treatment of bleeding with simultaneous combination of two endoscopic techniques has proved to be more efficient than monotherapy. None of the published comparative studies of various contact coagulation modalities have confirmed the superiority of one of these techniques over the others. AIM To comp...

We have previously shown that cancer cells can form an intravascular niche where they can proliferate and undergo apoptosis as well as traffic and extravasate. In the present study, green fluorescent protein (GFP) was expressed in the cytoplasm of HT-1080 human fibrosarcoma cells, and red fluorescent protein (mCherry), linked to histone H2B, was expressed in the nucleus to further investigate i...

This study evaluated the effects of Mesobuthus eupeus (Me) scorpion venom on inflammatory response following injection. Additionally, the present study examined whether immunotherapy at specific time intervals would be effective on inflammatory response after Me venom inoculation. Animals were divided randomly into four groups: the first group received LD50 of venom and the second and third gro...

BACKGROUND Neuronal damage leads to capillary degeneration in an N-methyl-D-aspartate (NMDA)-induced retinal degeneration model; however, the mechanisms underlying this phenomenon are not fully understood. The phosphatidylinositol 3-kinase (PI3K)/Akt signaling pathway has been recognized as an intracellular pro-survival signaling system. Therefore, we used the PI3K inhibitors LY294002 and wortm...

Hydrogen fuel is the cleanest fuel available. This fuel can be used as an additive in the diesel engine. Diesel engines have the advantages of strong power, high thermal efficiency and low fuel costs. There have been extensive studies on the use of hydrogen fuel in diesel engines in recent years. However, the simultaneous effect of using gaseous hydrogen fuel and changing injection strategy nee...

Iatrogenic femoral artery pseudoaneurysms (IFAPs) are not uncommon due to the increase in various minimally-invasive endovascular procedures. Percutaneous thrombin injection is an established technique for large pseudoaneurysms. When ultrasound-guided compression of aneurysmal neck feasible, percutaneous can be combined with balloon occlusion prevent leakage into parent artery. We describe a IF...

Abstract This work focuses on the study novel hybrid method of simultaneous spraying from two different materials (Al 2 O 3 and TiO ) by means suspension plasma (SPS) using submicron powder water suspension. The goal was to attempt deposition intermixed alumina-titania coatings, namely: Al + wt.% , 13 40 . Such compositions are already used but in form conventionally sprayed with micrometer-siz...