background: ccl22 is a chemokine that induces the migration of th2- and regulatory t cells to the inflammatory sites. the aim of this study was to investigate the association of a single nucleotide polymorphism (snp), rs4359426, in ccl22 gene, with multiple sclerosis (ms) in patients from southeast of iran. materials and methods: the blood samples collected from 150 patients with ms and 150 hea...

Abstract Objectives Free DNA is used as a cancer biomarker due to its low cost, high applicability, and fast, reliable results compared invasive methods. This study aimed evaluate the quantification of plasma-free after long-term storage conditions perform qualification through single nucleotide polymorphism (SNP) screening based on this DNA. Methods Plasma-free samples were quickly isolated fr...

Rice is the staple food in Republic of Guinea. However, its production seriously hampered by iron toxicity. The fight against this stress necessarily involves search for tolerant or resistant varieties. study aims to determine quantitative trait locus (QTL) associated with tolerance toxicity and identify genotypes Thus, 90 local rice accessions collected two regions Guinea high were evaluated u...

BACKGROUND The recent advent of genome-wide molecular platforms has facilitated our understanding of the human genome and disease, particularly copy number aberrations. We performed genome-wide single nucleotide polymorphism-array in hereditary coagulopathy to delineate the extent of copy number mutations and to assess its diagnostic utility. DESIGN AND METHODS The study subjects were 17 pati...

OBJECTIVE This study aims to investigate the single nucleotide polymorphisms (SNPs) of 5,10-methylenetetrahydrofolate reductase (MTHFR) gene and neural tube defects (NTDs) in Chinese population. METHOD A total of 271 NTDs cases and 192 healthy controls were used in this study. Fifty-two selected single nucleotide polymorphism (SNP) sites in the MTHFR gene were analyzed with next-generation se...

leptin (lep), the expression product of the obese gene produced primarily in the adipose tissue, is related to feed intake, growth and lipid metabolism. the aim of this study was to study the possible association between polymorphism of the lep gene with growth and carcass traits among three iranian sheep breeds of the shal, zandi and zel varieties. a total of 180 purebred animals of the shal, ...

urokinase might play a role in the formation of kidney stones. this study was done to determine the association between +4065 t/c polymorphism at the 3′-untranslated region of urokinase gene and calcium kidney stones. this case-control study was carried out on 70 cases with a history of calcium kidney stones and 70 controls from the baqiyatallah hospital of tehran in 2013. the study of polymorp...

conclusions lepr q223r polymorphisms may confer a significant risk of nafld and coronary atherosclerosis. the a allele in the k109r polymorphism might be considered an independent risk factor for coronary atherosclerosis in nafld patients. objectives to investigate the association of lepr polymorphisms at q223r and k109r with the risks of nafld and coronary atherosclerosis in the chinese han po...

ABCC11 is reported to be associated with breast cancer. However, whether ABCC11 polymorphisms relate to breast cancer risk remains unclear. This study aimed to evaluate any association of a single nucleotide polymorphism (SNP), rs17822931, in ABCC11 with breast cancer in Koreans. Genomic DNA samples of 170 women with breast cancer and 100 controls were assessed for SNP rs17822931 of ABCC11 by s...