Mechanisms leading to the obstruction of the microcirculation in sinusoidal obstruction syndrome (SOS) have been unclear. Because this occurs at the onset of disease, this is a potential key target for therapeutic intervention. Rats were treated with monocrotaline with or without continuous intraportal infusion of glutathione and were studied at 0.5, 1, 2, 4, 6, and 10 days after monocrotaline ...

An SN (sinusoids plus noise) model is a spectral model, in which the periodic components of the sound are represented by sinusoids with time-varying frequencies, amplitudes and phases. The remaining non-periodic components are represented by a filtered noise. The sinusoidal model utilizes physical properties of musical instruments and the noise model utilizes the human inability to perceive the...

Torque sharing function (TSF)-based switched reluctance motor (SRM) control is an effective approach to minimize torque ripple and maximize efficiency. This study investigated the influence of rotor geometry overcome inherent current tracking error used TSFs. Parameters TSF were optimized according several objectives. A finite element method simulation model was built verified evaluate objectiv...

In this paper, a relation between the elementary symmetric functions on the frequencies of multi-sine wave signal and its multiple integrals is proposed. In particular, such relation is useful to obtain a closed-form expression for the frequencies estimation. The approach used herein is based on the algebraic derivative method in the frequency domain, which allows to yield exact formula in term...

This study describes the use of a biofeedback method for the noninvasive study of baroreflex mechanisms. Five previously untrained healthy male participants learned to control oscillations in heart rate using biofeedback training to modify their heart rate variability at specific frequencies. They were instructed to match computer-generated sinusoidal oscillations with oscillations in heart rat...

Gaseous monoxides such as nitric oxide (NO) and carbon monoxide (CO) have recently attracted great interest as a regulator of cell and organ functions. When exposed to endotoxin, cytokines or ischemia-reperfusion, the liver produces larger amounts of NO than those in the control via the activity of inducible NO synthase which can alter a variety of organ functions such as sensitivity of vascula...

The fixed dimension modified sinusoidal model (FDMSM) was recently proposed as an attractive candidate for compact representation of audio signals in adverse conditions. This paper aims to study the capability of the FDMSM signal representation for analysis and synthesis of speech mixtures as well as noisy audio signals corrupted by highly colored noise of babble and harmonic. Extensive simulat...

Auditory brainstem responses were measured in five normal-hearing subjects, using single-cycle sinusoids at octave frequencies ranging from 250 to 2000 Hz. These sinusoids, gated with Blackman functions, were presented either at 0 or 180 degree phase and were varied in level from 90 dB SPL to threshold in 10-dB steps. Stimulus phase affected wave V latencies for low-frequency stimuli, with the ...

In many practical applications, it turned out to be efficient to assume that the signal or an image is sparse, i.e., that when we decompose it into appropriate basic functions (e.g., sinusoids or wavelets), most of the coefficients in this decomposition will be zeros. At present, the empirical efficiency of sparsity-based techniques remains somewhat a mystery. In this paper, we show that fuzzy-...