objective(s): response surface methodology (rsm) by central composite design (ccd) was applied to statistically optimize the preparation of rutin-quercetin (ru-qr) dual drug loaded human hair keratin nanoparticles as well as evaluate the characteristics. materials and methods: the effects of three independent parameters, namely, temperature (x1:10-40 c), surfactant (x2: sds (1), sls (2), tween-...

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In inspection and workpiece localization, sampling point data is an important issue. Since the devices for sampling only sample discrete points, not the completely surface, sampling size and location of the points will be taken into consideration. In this paper a method is presented for determining the sampled points size and location for achieving efficient sampling. Firstly, uncertainty analy...

This paper proposes a bus line capacity optimization design model considering the scale of multiple vehicles, which is achieved by minimizing system operating costs and user costs. The proposed takes into account difference passenger demand in different periods, can get optimal headway delivery reserve plan. In order to prove that method effectively minimize cost, we solved numerical example co...

In this paper, the discrete method of eigenvectors of covariance matrix has been used to weight minimization of steel frame structures. Eigenvectors of Covariance Matrix (ECM) algorithm is a robust and iterative method for solving optimization problems and is inspired by the CMA-ES method. Both of these methods use covariance matrix in the optimization process, but the covariance matrix calcula...

In the present study, Fe3O4 super paramagnetic nanoparticles were synthesized via co-precipitation of Fe3+ and Fe2+ chloride salts in the presence of ammonia Solution. The product was characterized by Fourier Transform Infrared spectroscopy (FT-IR), Transmission Electron Microscopy (TEM), and zeta–potential particle size distributing methods. The synt...

Computational cost of metaheuristic based optimum design algorithms grows excessively with structure size. This results in computational inefficiency of modern metaheuristic algorithms in tackling optimum design problems of large scale structural systems. This paper attempts to provide a computationally efficient optimization tool for optimum design of large scale steel frame structures to AISC...

The ubiquity of modular structure in real-world complex networks is being the focus of attention in many trials to understand the interplay between network topology and functionality. The best approaches to the identification of modular structure are based on the optimization of a quality function known as modularity. However this optimization is a hard task provided that the computational comp...

copper smelting slags are hard materials. therefore,to recover their copper by flotation method, grinding should be carried out to obtain optimal particle size. copper smelting slags in the bardeskan district, with work index of 16.24 kwh/st, were grinded for 65 minutes to reach an acceptable degree of freedom for the flotation tests, with particle size of 80%, smaller than 70 μm. with this gri...