Enteropathic arthritis (EA) is a spondyloarthritis (SpA) which occurs in patients with inflammatory bowel diseases (IBDs) and other gastrointestinal diseases. Diagnosis is generally established on the medical history and physical examination. It was, generally, made according to the European Spondyloarthropathy Study Group (ESSG) criteria. Rheumatic manifestations are the most frequent extraint...

Collagen vascular diseases (CVDs) like systemic lupus erythematosus (SLE), rheumatoid arthritis, Sjogren syndrome (SS), and scleroderma are immunologically mediated disorders that typically have multisystem involvement. Although clinically significant liver involvement is rare, liver enzyme abnormalities are common in these patients. The reported prevalence of hepatic involvement in SLE, histop...

RoTH, M., in Medical and Clinical Aspects of Ageing, ed. H. T. Blumenthal, New York, Columbia University Press, 1962. SJOGREN, T., LARRSON, T., and JACOBsSON, G., 'A clinical, genetic and statistical study of senile dementia', Acta Psychiat. Scand., Supp. 167, 1963. TOMLINSON, B. E., and BLESuSE, G., Senile Plaques and Intellectual Deterioration in old age. Psychiatric Disorders in the Aged, Ge...

Menopause is the physiological process of cessation of normal menstruation occurring in the fifth decade of life in women. This leads to certain hormonal variations which results in few clinical systemic manifestations along with oral symptoms. The main oral symptoms include oral dryness, mucosal lesions such as lichen planus, benign pemphigoid, Sjogren syndrome and burning mouth syndrome with ...

Sjogren-Larsson syndrome (SLS) is a rare autosomal recessive neurocutaneous disorder with worldwide incidence of 0.4 per 100,000 people. It is characterized by the triad of congenital ichthyosis, spastic diplegia or quadriplegia, and mental retardation. Herein we report a 2-year-old male child with SLS, asthma, and recurrent pneumonia. SLS was confirmed by a molecular genetics study that reveal...

This work has its origin in the Fellowship thesis for the Royal College of Veterinary Surgeons of one of us. We would like to thank the thesis supervisor Peter Lee for his invariably prompt and helpful criticisms of this work. We would like to thank Niclas Sjogren (latterly of AstraZeneca Statistics Department) for the fruitful discussions of the ideas from which this work came. Mr. Christopher...

Walls & Negroni (1966) reported the isolation in tissue culture of a transformed but non-malignant clone of cells from a polyoma virus-induced fibrosarcoma of C3H Bi mice. These cells, when inoculated into C.AH Bi mice, did not grow as tumours but immunized the animals against malignant cells derived from the same fibrosarcoma. Furthermore the serum from mice thus immunized prevents the growth ...