نتایج جستجو برای: skin factor
تعداد نتایج: 1021875 فیلتر نتایج به سال:
The skin, being the largest organ of the body, functions as a barrier between our body and the environment. It is consistently exposed to various exogenous and endogenous stressors (e.g., air pollutants, ionizing and non-ionizing irradiation, toxins, mitochondrial metabolism, enzyme activity, inflammatory process, etc.) producing reactive oxygen species (ROS) and physical damage (e.g., wounds, ...
Blockade of TGF-β/Smad signaling by the small compound HPH-15 ameliorates experimental skin fibrosis
BACKGROUND Transforming growth factor-β (TGF-β)/Smad signaling is well known to play a critical role in the pathogenesis of systemic sclerosis (SSc). We previously developed an artificial molecule, the histidine-pyridine-histidine ligand derivative HPH-15, which may have an antifibrotic effect. The purpose of the present study was to clarify the effects of this drug in human skin fibroblasts an...
N atural ageing of the skin is enhanced by environmental factors. Solar UV exposure is one of the main exogenous factors that is participating in that process and that can lead to photoageing, immunosuppression, and photocarcinogenesis. Using a new RSF method to determine UVinduced free radical injuries in the skin, it is possible to quantify the protective effect of sunscreens and UV-filters. ...
BACKGROUND Allogeneic skin grafts onto C57BL/6 mice are rejected, and the rejected skin is replaced by surrounding skin with black hair. In contrast, syngeneic skin grafts are tolerated, and gray hair grows on the grafts. METHODS To explore the mechanism of gray hair growing on the tolerated skin grafts, we prepared full-thickness skin (2-cm square) autografts, 2 (2 cm + 2 cm) horizontal or v...
Electronic skin (E-skin) is increasingly utilized in modern society, yet current E-skin technology suffers from issues, such as opacity, hardness, and fragility. To address these challenges, a novel was developed using polyurethane (PU) the matrix material silver nanowires (AgNWs) sensing material. By leveraging small degree of microphase separation lack crystallization PU, combined with approp...
Costimulatory signals and growth factor signals play a key role in commanding T cell activation and T cell effector function. However, how costimulatory signals and growth factor signals interact and integrate into the activation program of CD4(+) and CD8(+) T cells during the allograft response remains poorly defined. In the present study we found that either CD4- or CD8-deficient mice can vig...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید