Background: Hyper IgE syndrome (HIES) is a rare primary immune deficiency, described as Job`s syndrome characterized by increased serum levels of IgE, eczema, recurrent cutaneous and pulmonary infections. In this paper, we presented a case of Hyper IgE syndrome.Case Presentation: A 16-year-old Iranian boy presented with a one year history of skin lesions in knees and elbows was diagnosed of pso...

intravenous drug use (idu) is a frequent route of infection transmission, especially during the recent decades. numerous studies have addressed the increasing frequency of idu-associated infections such as hepatitis and aids. the present study was achieved to determine the prevalence of idu-associated infections in 3 teaching hospitals in iran. materials and methods for this descriptive study, ...

CONTEXT Cutaneous infections are common in wrestlers. Although many are simply a nuisance in the everyday population, they can be problematic to wrestlers because such infections may result in disqualification from practice or competition. Prompt diagnosis and treatment are therefore important. EVIDENCE ACQUISITION Medline and PubMed databases, the Cochrane Database of Systematic Reviews, and...

Objective(s) Human papillomavirus (HPV) infections are related to the genesis of various benign lesions and some malignant tumors, but no clear relationship has been identified so far between the subtypes of HPV and skin tag. Materials and Methods The present case-control study was designed to detect the existence of low risk and high risk HPV types in lesions of 50 patients with skin tag (c...

Community-acquired methicillin resistant Staphylococcus aureus (MRSA) usually causes skin and soft tissue infections. However, community-acquired methicillin resistant S.aureus has been identified as a causative agent of many invasive infections like necrotizing fasciitis, pneumonia and bacteremia. Risk factors such as immunodeficiency and skin and soft tissue infections have been identified fo...

BACKGROUND In the tsunami catastrophe in Thailand in 2004, several thousand Swedish tourists were injured, with contaminated crush trauma of the legs being the main cause of injury among the survivors. METHODS Patient and laboratory data for those who received hospital care in Stockholm and Gothenburg and contracted late-onset infections due to rapid-growing mycobacteria were reviewed retrosp...

Infections caused by drug-resistant pathogens are on the rise. Daptomycin, a cyclic lipopeptide with activity against most Gram-positive pathogens, including vancomycin-resistant enterococci and methicillin-resistant Staphylococcus aureus, is a newly US-FDA approved antimicrobial for complicated skin and skin structure infections (cSSSI). Daptomycin has a unique mechanism of action that results...

Methicillin-resistant Staphylococcus aureus has emerged in the community among patient populations without traditional antibiotic resistance risk factors and is causing a variety of clinical syndromes, in particular skin and soft tissue infections. These infections can range from minor skin involvement that can be treated in an outpatient setting to more serious infections such as necrotizing f...

Topical fungal infections can become severe if left untreated. Efficient treatment modalities for topical fungal infections aid the penetration of antifungal agents deep into viable skin layers. Terbinafine is a fungicidal agent that inhibits ergosterol, an essential fungal component. The main objective of this study was to evaluate skin permeation and retention of a terbinafine-loaded solution...

Skin and Soft Tissue Infections (SSTI) resulting from cat bites most commonly occur due to Pasteurella infection. However, other pathogens such as Β-Hemolytic Streptococci