Cutaneous T-cell lymphoma (CTCL) encompasses leukemic variants (L-CTCL) such as Sézary syndrome (SS) and primarily cutaneous variants such as mycosis fungoides (MF). To clarify the relationship between these clinically disparate presentations, we studied the phenotype of T cells from L-CTCL and MF. Clonal malignant T cells from the blood of L-CTCL patients universally coexpressed the lymph node...

Background. Transplant recipients require immunosuppression to prevent graft rejection. This conveys an increased risk of malignancy, particularly skin tumours. There is a need for up-to-date data for the South of England. Method. Pathology records were reviewed for 709 kidney transplant recipients on immunosuppression at our hospital from 1995 to 2008. Skin tumours were recorded/analysed. Resu...

Cancer is the second leading cause of death in the United States. The majority of cases are caused by sporadic somatic mutation, which leads to cellular transformation over time. Therefore, cancer gene identification is a major focus of current research efforts. Understanding how key driver mutations result in cancer could lead to the design of better targeted therapies. The Sleeping Beauty (SB...

Background: Percutaneous treatment has been widely used in low flow vascular malformations. However, surgery still an important role the management of these patients.Objective: The aim this study is to assess indications for malformations, as well safety, efficacy, and recurrence rate.Patients Methods: A total 33 patients with malformations were enrolled study. Duplex ultrasonography magnetic r...

Cutaneous vasculitis may be associated with malignancies, and may behave as a paraneoplastic syndrome. This association has been reported in a variable proportion of patients depending on population selection. We conducted the current study to assess the frequency, clinical features, treatment, and outcome of paraneoplastic vasculitis in a large unselected series of 766 patients with cutaneous ...

Background: Histoplasmosis is a disease caused by fungus called Histoplasma capsulatum. Several studies reported cases of histoplasmosis that resembled malignancy [3]. . It fact the clinical syndrome neoplastic not limited to malignancy, so infectious diseases should be considered in differential diagnosis. Method: This descriptive research with consecutive samples. The sample was patients lung...

Eosinophilic dermatosis of hematologic malignancy is a rare papulovesicular eruption that presents in patients with hematoproliferative disorders, particularly chronic lymphocytic leukemia. A 59-year-old woman with chronic lymphocytic leukemia who developed eosinophilic dermatosis of hematologic malignancy mimicking varicella zoster infection is described. PubMed database was searched with the ...

Cutaneous squamous cell carcinoma is a malignant tumour of the keratinising cells epidermis or its appendages. It constitutes 20% skin malignancy. UV radiation exposure most common cause cancer with sun exposed face and upper trunk being site for occurrence. Long term to chemical carcinogen, burn scar, chronic ulcer among other risk factors. Skin biopsy mainstay diagnosis in suspected lesion SC...