In present PET/CT scanners, PET attenuation correction is performed by relying on the information given by CT scan. In the CT-based attenuation correction methods, dual-energy technique (DECT) is the most accurate approach, which has been limited due to the increasing patient dose. In this feasibility study, we have introduced a new method that can implement dual-energy technique with only a si...

The feasibility for speed of sound dispersion (SOSD) imaging was investigated here. A through transmission new method for measuring the SOSD was utilized. With this method a long pulse comprising of two frequencies one being the double of the other is transmitted through the object and detected on its other side. SOSD projection images were obtained by scanning objects immersed in water using a...

Biopsy of breast lesions only visible on MRI may benefit from patient-specific finite-element modeling the breast. This requires acquisition heterogeneous elasticity distribution. An acoustically transparent pad has been developed which enables strain elastography imaging using ultrasound without need for additional force or pressure sensors. The is known a priori while change in thickness dete...

Quantitative ultrasound features such as the attenuation slope, sound speed and scatterer size, have been utilized to evaluate pathological variations in soft tissues such as the liver and breast. However, the impact of variations in the sound speed and backscatter due to underlying fat content or fibrotic changes, on the attenuation slope has not been addressed. Both numerical and acoustically...

X-ray phase-contrast imaging (XPCI) can dramatically improve soft tissue contrast in X-ray medical imaging. Despite worldwide efforts to develop novel XPCI systems, a numerical framework to rigorously predict the performance of a clinical XPCI system at a human scale is not yet available. We have developed such a tool by combining a numerical anthropomorphic phantom defined with non-uniform rat...

The mobility of soft tissue can cause inaccurate needle insertions. Particularly in steering applications that employ thin and flexible needles, large deviations can occur between pre-operative images of the patient, from which a procedure is planned, and the intra-operative scene, where a procedure is executed. Although many approaches for reducing tissue motion focus on external constraining ...

The aim of this study was to demonstrate the role of advanced fabrication technology across a broad spectrum of head and neck surgical procedures, including applications in endoscopic sinus surgery, skull base surgery, and maxillofacial reconstruction. The initial case studies demonstrated three applications of rapid prototyping technology are in head and neck surgery: i) a mono-material parana...

PURPOSE A phantom study was conducted to evaluate the feasibility of body contour definition with Compton scatter photons from external sources of technetium-99m pertechnetate (Tc-99m) to create a fusion image of CT and SPECT images. METHODS External sources of 1 mCi (37 MBq) Tc-99m were placed on each collimator, and body-contour SPECT images were obtained with an energy window of 100 keV +/...