Solid organ transplantation is a life-saving intervention for patients suffering from end-stage failure. Although improvements in surgical techniques, standards of care, and immunosuppression have been observed over the last few decades, transplant centers to face problem an insufficient number organs concerning growing demand. An opportunity increase pool intended more frequent use extended cr...

Surgery is the most effective method to cure patients with solid tumors. New techniques in near-infrared (NIR) cancer imaging are being used to identify surgical margins and residual tumor cells in the wound. Our goal was to determine the optimal time and dose for imaging solid tumors using Indocyanine Green. Syngeneic murine flank tumor models were used to test NIR imaging of ICG at various do...

Vascular hyperpermeability contributes to morbidity in inflammation. Current methodologies for in vivo assessment of permeability based on extravasation of Evans Blue (EB)-bound albumin are cumbersome and often lack sensitivity. We developed a novel infrared fluorescence (IRF) methodology for measurement of EB-albumin extravasation to quantify vascular permeability in murine models. Vascular ...

Robustness is one of the fundamental characteristics of biological systems. Numerous reports have been published on how robustness is involved in various biological processes and on mechanisms that give rise to robustness in living systems (Savageau, 1985a, b, 1998; Barkai and Leibler, 1997; Alon et al, 1999; von Dassow et al, 2000; Bhalla and Iyengar, 2001; Csete and Doyle, 2002, 2004; Kitano ...

plant tissue culture refers to growing and multiplication of cells, tissues and organs of plants on defined solid or liquid media under aseptic and controlled environment. micropropagation allows rapid production of high quality, disease-free and uniform planting material. the micropropagation of high quality planting materials of ornamentals, and forest and fruit trees has created new opportun...

Robustness is one of the fundamental characteristics of biological systems. Numerous reports have been published on how robustness is involved in various biological processes and on mechanisms that give rise to robustness in living systems (Savageau, 1985a, b, 1998; Barkai and Leibler, 1997; Alon et al, 1999; von Dassow et al, 2000; Bhalla and Iyengar, 2001; Csete and Doyle, 2002, 2004; Kitano ...