Objective: To analyze the potential mechanism of Xinyi San in treating rhinitis through network pharmacology. Methods: In database Traditional Chinese Medicine Systems Pharmacology (TCMSP), chemical composition and targets were got, target genes extracted from GeneCards databases. Then we constructed protein-protein interactions (PPI) genes, then analyzed Key GO analysis KEGG analysis. Results:...

Fluoroscopy-induced chronic radiation dermatitis (FICRD) is a complication of fluoroscopy-guided intervention. It usually appears without preexisting acute and has delayed onset. Unfortunately, it difficult to treat, some patients need receive wide excision reconstruction surgery. Due lack standard treatment, investigating underlying mechanism needed in order develop an effective therapy. Based...

Background: Polycystic ovary syndrome (PCOS) is a common complex genetic endocrinopathy, affecting 5 - 10% of women at reproductive age. PCO granulosa cells seem to have abnormal responses to follicle- stimulating hormone (FSH). FSH is considered to be a pituitary glycoprotein that plays an important role during folliculogenesis as it promotes the proliferation and differentiation of granulosa ...

Our previous study demonstrated that an extract of Cordyceps militaris (CM) derived from Samia Cynthia ricini inhibits testosterone-induced prostate hypertrophy in animal model. However, the bioactive components CM modulate function cells have not been identified and characterized. To do this, present explored effective component(s) influences viability androgen-responsive LNCaP cancer androgen...

The canine mammary tumor system is receiving increas ing attention as a model system for drug testing and for experimental study of basic mammary biology. In order to contribute to this model system, the hormone sensitivity of three types of canine preneoplastic lesions was identified morphologically on the basis of in vitro responses of organcultured expiants to various hormone supplements. Dy...

This study was conducted to determine the effect of daily recombinant porcine somatotropin (rpST) injection (0 or 120 pg/kg BW) and dietary CP level of the feed (14 or 26% CP) on pancreatic characteristics of growing pigs. Daily injection of rpST did not affect pancreatic weight ( P = .885) but did decrease pancreatic amylase content ( P = .005). The ratios of amy1ase:protein and amy1ase:trypsi...

We explored the involvement of oxytocin receptor ( Oxtr )/transient-receptor-potential-vanilloid-1 TRPV1 ) genes and (Oxt) on adaptation skeletal muscle to cold stress challenge in mice. expression hypothalamic paraventricular (PVN), supraoptic nuclei (SON), hippocampus (HIPP) were evaluated by immunohistochemistry parallel with measurement circulating Oxt. The gene expressions soleus (SOL) tib...

Ultra-processed food and psychological stress have led to an increase in the new incidence of irritable bowel syndrome. Xiaoyao powder is a classic traditional Chinese medicine formula for improving secretion transportation gastrointestinal tract as well eliminating intestinal allergy syndrome clinical treatment. To investigate targets mechanisms action treatment this study, we investigated com...