Purpose We report a case of ophthalmomyiasis interna successfully removed in toto with pars plana vitrectomy. Observations An 84-year-old woman with recent close contact with lambs presented with a new floater. Examination revealed subretinal tracks pathognomonic for ophthalmomyiasis and a larva suspended in the vitreous. The larva was successfully removed in toto with pars plana vitrectomy b...

A case of Staphylococcus caprae endophthalmitis in a young patient following pars plana vitrectomy for symptomatic vitreous floaters is reported here. Recent literature suggests that there is an increasing trend of performing pars plana vitrectomy for symptomatic floaters. Although rare, the potential risk of endophthalmitis should be explicitly discussed with patients considering surgical inte...

OBJECTIVE To analyse patients' self-reported reasons for not adhering to physical activity referrals (PARs). DESIGN AND SETTING Data on 1358 patients who did not adhere to PARs were collected at 38 primary health care (PHC) centres in Sweden. INTERVENTION PHC providers issued formal physical activity prescriptions for home-based activities or referrals for facility-based activities. SUBJE...

UNLABELLED ParB proteins bind centromere-like DNA sequences called parS sites and are involved in plasmid and chromosome segregation in bacteria. We previously showed that the opportunistic human pathogen Streptococcus pneumoniae contains four parS sequences located close to the origin of replication which are bound by ParB. Using chromatin immunoprecipitation (ChIP), we found here that ParB sp...

Protease signaling in cells elicits multiple physiologically important responses via protease-activated receptors (PARs). There are 4 members of this family of G-protein-coupled receptors (PAR1-4). PARs are activated by proteolysis of the N terminus to reveal a tethered ligand. The rate-limiting step of PAR signaling is determined by the efficiency of proteolysis of the N terminus, which is reg...

PURPOSE To report a case of corneal ectasia secondary to pars planitis corneal endotheliopathy METHODS Clinical case description and proposed hypothesis regarding development of corneal ectasia RESULTS Eight-year-old male presented with 360° peripheral corneal endotheliopathy and edema, granulomatous keratic precipitates, and mild iritis OD. A progressive corneal ectasia then developed. Twe...

Implanting glaucoma tubes through the pars plana in the setting of a corneal transplant is becoming more common, and there are unique problems associated with such a procedure. A 42-year-old man with multiple previous eye surgeries presented with a nonfunctioning pars plana glaucoma tube. There was no view to the tube tip, but it was presumed to be clogged with fibrin. Intravitreal tissue plasm...

OBJECTIVE To present a case of a fracture of the unilateral pars interarticularis of the C2. METHODS There is confusion in the use of anatomic terminology of the pars interarticularis and pedicle of the C2 in literature. A fracture of the unilateral pars interarticularis of the C2 was diagnosed and treated nonsurgically by a Philadelphia collar. RESULT The patient was free of pain and obtai...