A multicompartment biologically based dynamic model was developed to describe the time evolution of methanol and its metabolites in the whole body and in accessible biological matrices of rats, monkeys, and humans following different exposure scenarios. The dynamic of intercompartment exchanges was described mathematically by a mass balance differential equation system. The model's conceptual a...

In this article, the multi-objective optimization of cylindrical aluminum tubes under axial impact load is presented.The absorbed energy and the specific absorbed energy (SEA) are considered as objective functions while the maximum crush load should not exceed allowable limit. The geometric dimensions of tubes including diameter, length and thickness are chosen as design variables. The Non-domi...

UNLABELLED The aims of this study were to examine the relationship between whole-body absorbed dose and hematologic toxicity and to assess the most accurate method of delivering a prescribed whole-body absorbed dose in (131)I-metaiodobenzylguanidine ((131)I-MIBG) therapy for neuroblastoma. METHODS A total of 20 children (1-12 y), 5 adolescents (13-17 y), and 1 adult (20 y) with stage 3 or 4 n...

Designs of CSCL (Computer Supported Collaborative Learning) activities should be flexible, effective and customizable to particular learning situations. On the other hand, structured designs aim to create favourable conditions for learning. Thus, this paper proposes the collection of representative and broadly accepted (best practices) structuring techniques in collaborative learning. With the ...

The lipolytic hypothesis of fat absorption advocated by Verzar and McDougall7 in 1936 maintains: that ingested fat undergoes emulsification to soap and complete hydrolysis to fatty acid and glycerol in the small intestine; that a solid pavement epithelial structure exists on the intestinal mucosal cells; that the fatty acids pass through the membrane as soluble complexes with bile salts, while ...

Of seven plant viruses tested, all except tobacco mosaic showed the phenomenon of photoreactivation, i.e. plants exposed to visible light after inoculation with preparations partially inactivated by ultraviolet radiation produced more local lesions than plants kept in darkness. Five straiIis of tobacco mosaic virus, which differed widely in their pathogenicity and other properties, were tested,...