STUDY DESIGN A prospective, randomized, double-blind clinical trial. OBJECTIVE To compare the efficacy of postoperative continuous epidural analgesia versus patient-controlled analgesia in patients undergoing lumbar fusion. SUMMARY OF BACKGROUND DATA Controversy remains regarding the optimal strategy for postoperative pain control. METHODS Fifty-four patients were divided into two treatme...

INTRODUCTION Epidural analgesia has become the most popular method for labor pain relief. Analgesia in Labor: Yes or No? Labor pain is a complex phenomenon with sensory, cognitive, motivational, emotional, social, and cultural variables. Pain and anxiety lead to adrenergic hyperactivity, hyperventilation, hypocapnia with reduced uteroplacental blood flow and uncoordinated uterine activity, so p...

Nimodipine, an L-type calcium channel blocker, can induce analgesia. However, it is not clear that this analgesic effect is at the level of spinal or supraspinal pain pathway. In addition, it has been reported that the analgesic effect of nifedipine, another L-type calcium channel blocker is related to the HPA axis, but there is no report indicating the role of this axis in the analgesic eff...

Melatonin has been suggested as a new natural pain killer in inflammatory pain and during surgical procedures. We designed this randomized double-blind controlled study to evaluate the analgesic efficacy and also optimal preemptive dose of melatonin in patients undergoing cesarean section under spinal anesthesia.One hundred twenty patients scheduled for cesarean section under spinal anesthesia ...

ANAESTHESIA ....................................... 3 Ether .......................................................... 3 Chloroform ................................................ 4 Initial reactions .......................................... 4 Methods of administration ......................... 5 Drawbacks of chloroform ........................... 6 Other inhalational agents ....................

Pain and symptom management at the end of life remains suboptimal.Pain physicians are uniquely placed to provide interventions for patients with difficult to manage pain.Interventions such as acupuncture, radiofrequency ablation, neurolysis together with regional analgesia including neuraxial techniques and spinal cordotomy may provide the patient with improved analgesia.

The safety, advantages, disadvantages and anesthetic agents used in the segmental technique of continous lumbar epidural analgesia for pain relief during labor and delivery are discussed in this article. The author describes the anesthetic management of an uncomplicated labor and vaginal delivery. Upon reading the Joint Commission on Accredita-tion of Hospitals' manual, it becomes obvious that ...

Neuraxial agents provide robust pain control, have the potential to improve outcomes, and are an important component of the perioperative care of children. Opioids or clonidine improve analgesia when added to perioperative epidural infusions; analgesia is significantly prolonged by addition of clonidine, ketamine, neostigmine or tramadol to single shot caudal injections of local anesthetic; and...

Hyperbaric bupivacaine is the most common drug used in spinal anesthesia for caesarean section. The aim of this study was to compare the effects of adding fentanyl to intrathecal bupivacaine on the onset and duration of spinal anesthesia and its effect on mother and neonate. Seventy healthy parturients with singleton pregnancy scheduled for elective cesarean section were randomly allocated to r...

OBJECTIVE This is a retrospective study of the role of postoperative epidural analgesia in major spinal surgical procedures. With the number and complexity of the procedures performed on the spine ever-increasing, this method of analgesia is becoming more important. METHODS Results of 74 consecutive cases of major spinal surgeries between January 2000 and January 2001 at the Spine Division, A...