Histochemical characterization of NADPH diaphorase positive neuronal pools in the rabbit lumbosacral segments was performed during and after transient spinal cord ischemia. Strongly enhanced staining of NADPH diaphorase positive structures appeared in the superficial dorsal horn, the pericentral region and in the neurons of the sacral parasympathetic nucleus at the end of 40 min of abdominal ao...

Case Report. Spinal Cord Ischemia Associated With Repair of a Ruptured Abdominal Aortic Aneurysm • Spinal cord ischemia is a rare complication of rupture of an abdominal aortic aneurysm or its emergency surgical treatment; only seven cases have been reported previously. A patient with this complication is described. It was characterized by postoperative total loss of all forms of sensation in t...

Case Report. Spinal Cord Ischemia Associated With Repair of a Ruptured Abdominal Aortic Aneurysm • Spinal cord ischemia is a rare complication of rupture of an abdominal aortic aneurysm or its emergency surgical treatment; only seven cases have been reported previously. A patient with this complication is described. It was characterized by postoperative total loss of all forms of sensation in t...

Case Report. Spinal Cord Ischemia Associated With Repair of a Ruptured Abdominal Aortic Aneurysm • Spinal cord ischemia is a rare complication of rupture of an abdominal aortic aneurysm or its emergency surgical treatment; only seven cases have been reported previously. A patient with this complication is described. It was characterized by postoperative total loss of all forms of sensation in t...

Coarctation and occlusion of the aorta is a rare condition that typically presents with hypertension or cardiac failure. However, neuropathy or myelopathy may be the presenting features of the condition when an intraspinal subarachnoid hemorrhage has compressed the spinal cord causing ischemia. We report two cases of middle-aged males who developed acute non-traumatic paraplegia. Undiagnosed co...

BACKGROUND/AIMS Dexmedetomidine has beneficial effects on ischemia reperfusion (I/R) injury to the spinal cord, but the underlying mechanisms are not fully understood. This study investigated the effects and possible mechanisms of dexmedetomidine on blood-spinal cord barrier (BSCB) disruption induced by spinal cord I/R injury. METHODS Rats were intrathecally pretreated with dexmedetomidine or...

Cardiac sympathetic afferent fibers activated during coronary occlusion exert an excitatory influence on sympathetic discharge to the heart in cats after spinal cord section. The significance of this cardiocardiac sympathetic reflex response during myocardial ischemia in animals with an intact neuraxis is unknown. We studied the responses of efferent cardiac sympathetic nerve activity (CSNA), a...

spinal cord injury (sci) is a devastating condition, with sudden loss of sensory, motor, and autonomic function distal to the level of trauma. the primary mechanical trauma causes necrosis, edema, hemorrhage, and vasospasm. a cascade of secondary pathophysiological mechanisms is induced, including ischemia, apoptosis, fluid and electrolyte disturbances, excitotoxicity, lipid peroxidation, produ...

BACKGROUND Lower limb paralysis occurs in 11% of patients after surgical procedure of thoracic or thoracoabdominal aneurysms and is an unpredictable and distressful complication. The aim of this study was to investigate the effects of tetramethylpyrazine (TMP), an intravenous drug made from traditional Chinese herbs, on the neurologic outcome and histopathology after transient spinal cord ische...

Intramedullary spinal cord arteriovenous malformation (AVM) can be a devastating disease. It is not usually amenable to surgery without producing severe neurologic deficit. Previously, the risk of cord ischemia was considered a contraindication to therapeutic embolization. Three patients with intramedullary spinal cord AVMs were examined and treated using polyvinyl alcohol foam, mixed with Gelf...