Metastatic spinal tumours are the most common type of bone metastasis. Various methods have been used to treat metastatic spinal lesions, including radiotherapy, chemotherapy, isotope therapy, bisphosphonate therapy, analgesics, and surgery. Conservative treatments such as radiotherapy and chemotherapy are not appropriate and usually are ineffective in patients with vertebral fractures and/or s...

despite of the fact that the vulva contains a high density of apocrine and anogenital mammary glands in addition to eccrine glands and folliculosebaceous units, the benign vulvar adnexal tumours are rare. though the varied clinical presentation and diverse histopathological spectrum of vulvar neoplasms has amazed the pathologists, only few studies have been reported in literature. the present f...

BACKGROUND The relative frequency of compressive and non-compressive myelopathies and their aetiologies have not been evaluated extensively in most sub-Saharan African countries. The case of Cameroon is studied. METHODS Admission registers and case records of patients in the neurology and neurosurgery departments of the study hospital were reviewed from January 1999 to December 2006. RESULT...

The tumours to be considered here are those arising primarily in the meninges, or gaining access to them as secondary growths. It will be necessary to consider not only the dura and leptomeninges that invest the brain and spinal cord, but also their extensions into the brain as the tela choroidea and stroma of the choroid plexuses, and the sheaths of the perforating blood-vessels that form the ...

510 cases of surgical lymph node biopsies during a five year periode are reviewed with the following conclusionsthe lymph node biopsy constitues 5% of all the surgical biopsies, the cervical and axillary lymph nodes are the most commonly biopsicd nodes due to their easy accessibility and due to the fact that they drain the lymph from many vital organs: the next most commonly biopsied nodes are ...

Mediastinal neurogenic tumours generally arise as single benign lesions and their typical location is the costovertebral sulcus. In about 10% of cases mediastinal neurogenic tumours may extend to the spinal canal; occasionally they may extend to the cervical region and, more rarely, may be multiple or associated with other synchronous mediastinal lesions. The treatment of choice is surgical res...

Abstract BACKGROUND Spinal meningiomas account for 1.2-12 % of all and 25-45 spinal tumours. 20 intracranial, but only 4.6 recur requiring additional treatment. Whereas the classification intracranial has evolved considerably in recent years uses genetic epigenetic parameters, is based solely on histopathological findings. By embedding epi-/genetic features, prognosis could be significantly imp...

A retrospective study of 25 patients who presented with posterior fossa haemangioblastomas to the Northern Ireland Regional Neurosurgical Centre over the past 25 years has been carried out. The epidemiological and clinical features and the results after operative treatment are presented and compared with other series. Posterior fossa haemangioblastomas were more common in female than in male pa...

Pediatric spinal ependymomas (SEPN) are important albeit uncommon malignant central nervous system tumors with limited treatment options. Our current knowledge about the underlying biology of these tumors is limited due to their rarity. To begin to elucidate molecular mechanisms that give rise to pediatric SEPN, we compared the transcriptomic landscape of SEPNs to that of intracranial ependymom...

Hemangioblastomas are benign tumours affecting the central nervous system (CNS) as sporadic case or as manifestation of von Hippel Lindau disease (VHL), a neoplastic multistemic autosomal dominant syndrome predisposing to develop CNS and visceral lesions. Hemangioblastomas are predominantly originating in the cerebellum and in the cervical and thoracic spinal cord; localization at the cauda equ...