OBJECTIVE The label and detection of cells injected into target tissues is an area of focus for researchers. Iron oxide nanoparticles can be used to label cells as they have special characteristics. The purpose of this study is to examine the effects of iron oxide nanoparticles on human-derived amniotic membrane stem cell (hAMCs) survival and to investigate the magnetic properties of these nano...

Background Immunotherapy of cancer is an emerging field with the potential to improve long-term survival. Thus far, adoptive transfer tumor-specific T cells represents effective treatment option for tumors hematological system such as lymphoma, leukemia or myeloma. However, in solid tumors, efficacy low owing immunosuppressive microenvironment, on-target/off-tumor toxicity, limited extravasatio...

in this work, we report synthesis of surface modified superparamagnetic iron oxide nanoparticles (spion) by co-precipitation method using feso4.7h2o and fe2(so4)3.5h2o as precursors and trisodium citrate dihydrate as surfactant. surface modification of the as prepared samples was performed in pot by sol-gel precipitation method using tetraethoxysilane (teos). the structure, morphology, and magn...

Objective (s): SN38 is the prominent and effective anticancer drug for treating various types of human cancers such as colorectal, ovarian and lung cancers. SN38 is highly toxic, and due to its poor solubility in aqueous media, and low stability and hydrolysis at physiological pH, it has not been used as an anti-cancer drug. To overcome these problems, SN38 was conjugated with new nanocarriers ...

Introduction: All of the Imaging modalities have advantages and disadvantages alone. So if we want to have the best and perfect image, combining these modalities produces something we desired. PET-MR images consist of morphologic and metabolic data. MRI and PET provide high spatial and contrast resolution and high sensitivity and molecular information respectively. Hybrid PET-...