Thirteen cases are described of temporary malabsorption in adults presenting after an episode of apparent infective enteritis. Clinical features included diarrohea, anorexia, and weight loss. Investigations indicated diffuse impairment of function in the small bowel, including the ileum, with well-preserved mucosal morphology in the upper jejunum and a tendency to rapid folate depletion. Sponta...

Glycine has been used for many years as an orally administered test substance in the study of intestinal absorption. Most authors have utilized a technique measuring the total amino acid nitrogen of the blood at intervals after an oral dose of glycine, with the assumption that increases reflect the amount of glycine absorbed. Althausen, Doig, Uyeyama, and Weiden (1) have demonstrated the validi...

T HE MEGALOBLASTIC ANEMIA which is characteristically present in persons with advanced tropical sprue is usually due to a combined deficiency of folate and vitamin B12.1 Deficiency of vitamin B12 in this condition has been clearly demonstrated to be secondary to malabsorption of this vitamin.’ The factors responsible for folate deficiency are less well-defined. Impaired absorption of pharmacolo...

IT HAS BEEN ACCEPTED as an uindisputed fact that the parcnnteral administrationn of antiannemic factors is generally more effective inn the treatment of sprue than their oral administration because of poor intestinal absorptionn. The flat oral glucose tolerance curve, the low serum proteinis, the apparenit diminnished al)sorptionn of vitamin A amid of certaimn fats, the loss of is-eight, amid t...

T HE MEGALOBLASTIC ANEMIA which is characteristically present in persons with advanced tropical sprue is usually due to a combined deficiency of folate and vitamin B12.1 Deficiency of vitamin B12 in this condition has been clearly demonstrated to be secondary to malabsorption of this vitamin.’ The factors responsible for folate deficiency are less well-defined. Impaired absorption of pharmacolo...

BUMC PROCEEDINGS 2002;15:16–17 Celiac sprue, a gluten-induced enteropathy, was once considered primarily an immunologic disease of infants and children. Gluten is a protein found in grains, primarily wheat and barley. The ingestion of gliadin, a component of gluten, causes gastrointestinal symptoms including malabsorption and multiple nutritional deficiencies. Our understanding of this disorder...

refractory celiac disease (rcd) is when malabsorption symptoms and villous atrophy persist despite strict adherence to a gluten free diet (gfd) for more than 12 months and other causes of villous atrophy have been ruled out.  rcd is considered a rare disease and almost exclusively occurs in adults. persistent diarrhea, abdominal pain, weight loss are the most common symptoms in rcd. also, anemi...